Question

In: Anatomy and Physiology

Provide one example of negative feedback.

Provide one example of negative feedback.

Solutions

Expert Solution

Negative feedback is the mechanism by which if some factor becomes excessive or deficient, a series of changes are initiated that will return the factor toward a certain mean value, thus maintaining homeostasis.

One example for negative feedback mechanism is Secretion of thyroxine hormone by thyroid gland under the influence of thyroid stimulating hormone

  • Thyrotropin releasing hormone (TRH) produced by hypothalamus stimulates pituitary gland to produce thyroid stimulating hormne(TSH). TSH is released from pituitary gland stimulates the secretion of thyroxine hormone by thyroid gland. When thyroxine level increases in blood, it inhibits the secretion of Thyroid Stimulating Hormone from pituitary. As a result the secretion of thyroxine from thyroid gland decreases. On the other hand, if thyroxine secretion by the thyroid gland is less, the concentration of thyroxine in the blood decreases, which in turn stimulates the pituitary gland to release Thyroid Stimulating Hormone which in turn stimulates thyroid gland to secrete thyroxine.


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