Question

4

a. A mutation in the regulatory region of a gene gives it a new pattern of expression. Normally the wild type protein is produced only in the brain, the mutant form is found in many different tissues. This type of mutation is called a

a. reverse mutation

b. lethal mutation

c. gain-of-function mutation

d. conditional mutation

e. loss-of-function mutation

b. Suppose you have a mutation in a protein at codon 64 that changes a glycine codon to a valine codon. The mutant protein is unable to function. However, a second mutation, which changes codon 50 from an alanine codon to a threonine codon, is able to restore function. Which of the following is the appropriate term to describe the second mutation.

	a.	Intragenic suppressor mutation
	b.	Intergenic suppressor mutation
	c.	Silent mutation
	d.	Missense mutation
	e.	Reversion mutation

Answer 1

4. a. It's takes place when a particular natural or artificial stimulus is provided to create a condition.

b. Reversion mutation is 2 nd mutation nullifying effect of 1 st mutation.

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