A 42 year old woman was introduced to the Emergency Room with complaints of abdominal pain for the past few days. She was also reported her stools have been black and sticky. She suspected to have GI (gastro-intestinal) bleeding. According to her medical history, she was transfused with 2 units washed packed RBCs 6 months ago for the same symptoms. The CBC results were:

WBCs: 5.7 X 103/µl

RBCs: 2.95 X 106/µl

HGB: 6.3g/dL

Hematocrit: 19.8%

According to her anemic condition, she was admitted to the hospital for treatment and given 3 units of packed RBCs (each blood unit should increase hemoglobin level by 1g/dL, but she was given 3 units since she had an active GI bleeding). She is type B positive with a negative antibody screening {1} which means no antibodies were observed in her plasma. The 3 units were cross-matched and transfused without adverse reactions. One day later, she was discharged. Two days after discharge, she returned to the Emergency Room with yellowish eyes and skin (jaundice). The CBC at this time showed HGB = 5.8g/dL and elevated bilirubin level indicated hemolysis of RBCs. She was ordered with 2 units of packed red blood cells. At this time, the antibody screen was now positive {2}. Anti-JKb was found in her plasma and positive DAT was observed.

She was diagnosed with a delayed hemolytic transfusion reaction (DHTR) due to anti-JKb

1.       Discuss this condition DHTR?

2.       Why the first antibody screening {1} was negative? (Knowing that anti-JKb was present in her plasma from exposure of JKb positive blood via previous blood transfusion according to her medical history)? However, it is really negative since no immediate HTR was observed

3.       Why the second antibody screening{2} becomes positive after blood transfusion?

4.       If DAT was performed by gel-method, and positive mixed field result was observed. What does this mean?

Create a powerpoint presentation on Learning Together and managing group conflict.

After examining mohammad nassar and ordering and reviewing the results of an ECG test, Dr William's indicates that mohammad Nassar's heart appears to be normal. what factors might be contributing to mohammad Nassar's episodes of tachycardia?

3a. The ability for researchers to generalize the results of their study to the general population is called:

1. Internal validity
2. External validity
3. Response validity
4. Reliability

3b. If a screening test for a fast growing, deadly disease has been producing too many false negatives, which adjustment should you make to the screening tool?

1. Decrease sensitivity
2. Decrease specificity
3. Increase sensitivity
4. Increase specificity

3c. A screening test that (i) does not miss a lot of individuals with the disease, but (ii) inappropriately screens positive many individuals who do not have the disease, could be referred to as

1. High sensitivity/ high specificity
2. Low sensitivity/ low specificity
3. Low sensitivity / high specificity
4. High sensitivity/ low specificity

3d. A case-control study was performed to determine whether head injury was associated with an increased risk of brain tumors in children. Two hundred (200) cases with brain cancer were identified from the state cancer registry, and 200 controls were recruited from the same neighborhoods where the cases lived. The mothers of the children completed a questionnaire that asked them to describe their child’s past history of head injury. The investigators found that the mothers of the children with brain tumors reported a past head injury for 70 of the cases while a past history of head injury was reported in 30 of the controls. What type of bias was likely to have influenced the findings of this study?

1. Observer bias
2. Recall bias
3. Length bias
4. Surveillance bias

Pediatric Case Study Scenario history: Johnny is 6 years old, admitted late yesterday with exacerbation of asthma. Johnny has a history of asthma for 2 1/2 years. He has been admitted to the hospital exacerbation x3; no ICU admission. He was admitted due to coughing, expiratory wheezing, runny nose, and increasing shortness of breath that began shortly after a low-grade fever. Presenting signs: Temp 100.4, HR; 112, RR; 28, 02 Sat 91% Expiratory wheezing, intercostal, and subcostal retractions; unable to complete a sentence without shortness of breath. Peak flow meter- 60%.

1. What would you include in an Asthma Action Plan for Johnny?

2. What B-2 Agonists and Corticosteroids commonly used in the treatment of asthma?

ABO typing is determined by antigens located at the surface of RBCs membrane. These antigens are carbohydrates (sugars) in their structures. Different studies were reported the association between blood type and the tendency to be affected with Covid 19 (or at least the severity of symptoms in Covid positive patients vary according to their blood type).

On the other hand, blood type of person from which you get the virus plays a role in the aggressiveness of disease (this means that, if a patient with A blood type transmits the virus to type O person, the aggressiveness will not be the same as if the person getting the virus is also type A).

Discuss these aspects Fully??

List 20 factors that will ensure food security for when the world population reaches 10-12 billion people. Explain all factors

One of the important skills that hospital administrator must possess is the analytical skills which involves the ability to:

Coordination is becoming an important function to hospital managers because of the followings except……….

1. What are the risks that arise in hospital patients receiving infusion of a specific drug concentration over time?

Professional Platform for Ethics and Leadership(My platform is nursing)

I need you to write on the Primary influences (childhood and adult) of the above asked

Don't copy from another site

500 words

Ethical leadership and professional development plan. Include both positive and negative aspects of your character that emerge when you are in a position of authority
my profession is nursing

Briefly write the histological features of abomasum (true stomach) of goat.

A hospital-based case-control study of alcohol consumption in relation to a particular type of cancer was conducted. The investigators selected patients admitted for conditions that were not related to alcohol consumption as the control group. 200 controls were individually matched to 200 cases by age and sex. Alcohol consumption was assessed by an in-person interview conducted by a trained interviewer in the hospital (suggested length, a brief paragraph each for 1) to 3) below).

1. Using epidemiological terminology, describe three potential biases which you may be concerned about in this example, and why you think such biases might have arisen.

2. For each of the three sources of bias, briefly describe steps that could be taken to control or remove the potential biases in the design of your study and analysis of study data.

3. Why was it important that the control group included patients with conditions that were not related to alcohol consumption?

4. The matched odds ratio for the association between alcohol consumption and cancer was 2.0.  Given that, create a contingency table that would result in this odds ratio based upon the matched data (note:  there are many possible correct responses to this question).

We have provided a list of three topics below.  Select one that is of interest to you.  For that topic, imagine that you are developing a CIHR Project Grant.  Part of that grant will be to create a thorough and convincing knowledge translation (KT) plan for your study and its findings.  In 400 words or less (that is the maximum space you will have on this grant application), please outline the essential elements of your KT plan as would be included in your grant.

Topic 1.  A randomized trial to investigate a new antiemetic therapy (vs. standard care) for use in the treatment of breast cancer patients undergoing chemotherapy

Topic 2.  A study of gender identity, emotional wellbeing, and academic achievement in Ontario high school students

Topic 3.  A study of occupational of safety conditions on fruit and vegetable farms in the Niagara region and the health of migrant workers