2. Dengue fever vaccine, Dengvaxia, is currently approved for use in those ages 9 to 45 who live in areas with a high incidence of dengue fever and given in three doses over the course of 12 months. What are your thoughts?

3. What is RA 9482 and its salient points? As a nursing student, to prevent rabies, what to you is responsible pet ownership?

4. What are the differences and similarities of Candidiasis and Chlamydia? Why Infectious Mononucleosis is called kissing disease?

5. Do you think the patient will die in AIDS or will die in opportunistic infections. If in AIDS why and if it is opportunistic infections, what are those?

Discussion: Pharmacokinetics and Pharmacodynamics

As an advanced practice nurse assisting physicians in the diagnosis and treatment of disorders, it is important to not only understand the impact of disorders on the body, but also the impact of drug treatments on the body. The relationships between drugs and the body can be described by pharmacokinetics and pharmacodynamics. Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body. When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharamcodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease. In this Discussion, you reflect on a case from your past clinical experiences and consider how a particular patient’s pharmacokinetic and pharmacodynamic processes altered his or her response to a drug.

To prepare:

• Review this week’s media presentation with Dr. Terry Buttaro, as well as Chapter 2 of the Arcangelo and Peterson text, and the Weitzel et al (2014) article in the Learning Resources. Consider the principles of pharmacokinetics and pharmacodynamics.
• Reflect on your experiences, observations, and/or clinical practices from the last five years. Select a case from the last five years that involves a patient whose individual differences in pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug. When referring to your patient, make sure to use a pseudonym or other false form of identification. This is to ensure the privacy and protection of the patient.
• Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.
• Think about a personalized plan of care based on these influencing factors and patient history in your case study.

With these thoughts in mind:

By Day 3

Post a description of the case you selected. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient from the case you selected. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case.

2. Compared with the nearest evolutionary relative, the chimpanzee, the human has a brain that is
huge. At a point in the past, a common ancestor gave rise to the two species of humans and
chimpanzees. That evolutionary history is long and is still an area of intense study. But
something happened to increase the size of the human brain relative to the chimpanzee.
Read this article in which the author explores the current understanding of why this happened.

Article link: https://blogs.scientificamerican.com/guest-blog/how-did-human-brains-get-to-be-sobig/

Answer: According to one hypothesis about the expansion of brain size, what tissue might have been sacrificed so energy was available to grow our larger brain?
Based on what you know about that tissue and nervous tissue, why would there be a trade-off between them in terms of
energy use?

Read the case study below:

Shane is a 12-year-old 7th grader at Willow Creek Middle School. He received strong grades until 4th grade. He is currently failing 5 of his 6 classes. The only class he is not failing is PE. His teachers report that Shane does not pay attention and have stated that he “frequently appears preoccupied.” Shane’s mom is a single parent and Shane does not have any contact with his dad. There are reports that Shane’s father had “mental problems” before he abandoned his family two years ago. In addition, before the father left the family it is suspected that Shane (and his siblings) witnessed frequent violent domestic battles. On at least one occasion these fights resulted in his mother’s hospitalization. Ms. Jenkins has three other children: John a 17-year-old boy, Matt a 10-year-old boy and Jennifer an 8-year-old girl. Matt and Jennifer are doing okay in school, but John is in serious trouble due to truancy and substance abuse. Both Shane and John have frequent arguments with their mother, each other, and with their siblings. Shane has a group of friends who he spends most evenings with. His mother has not been able to impose a curfew.

Answer the following questions:

1. To what extent do you feel that consultation services will be able to address these challenges?

2. Do you think referral to a community mental health care provider is indicated? If “NO,” when (under what circumstances) would such a referral become appropriate? If “YES,” to which type of mental health professional would you refer the student?

3. Would group counseling be appropriate for this student? If “YES,” what type of group? If “NO” under what circumstances would this intervention become appropriate?

4. Would individual counseling be appropriate for this student? If “YES,” what would be the focus of the counseling sessions? If “NO” under what circumstances would this intervention become appropriate?

5. At any point in this student’s history would crisis intervention have been (or currently be) appropriate? If ‘YES,” what would be the primary goal of such intervention?

6. Might this student be eligible for special education according to ED eligibility criteria? (you will need to research ED eligibility) Explain your reasoning.

In your own words, what is intersectionality? Tell me how you would apply intersectionality to your own life and experiences?

Cellular adaptation refers to changes made by a cell in response to adverse environmental changes. List the five (5) major types of cellular adaptation and write one sentence for each explaining what it is.

Need 600 Words long correct Answer:

Assignment: Choosing a drug delivery system for the best patient outcome

As a Pharmacist you have been asked to recommend a drug delivery system that can be administered for a patient. You will need to communicate to your peers and other healthcare providers why you have chosen this particular drug delivery system for this patient. You will need to:

A. Choose a disease state that you would like to research.

B. Decide on your patient profile/case study.

C. Justify your reasons why you have chosen this particular drug delivery system for your patient.

Tips and Hints:

Think about all the information we have covered in lectures about the choice of drug delivery system.

Research your chosen disease state and what pharmacotherapy is used.

Think clearly about your chosen case study

a nurse is reviewing the laboratory results of a client who is at 20 weeks of gestation and has type 1 diabetes mellitus. which of the following findings should the nurse report to the provider?

A.) BUN 25 mg/dL

B.) Platelets 170,000/mm3

C.) HbA1c 6%

D.) HCT34%

Choose one medication allergy commonly seen in practice. What cross-sensitivities could patients with this medication allergy experience? What potential complications and reactions could this patient have and what treatment is available?

In lesson 2 for this week, you were asked to reflect on your understanding of health leadership and how this resonates with your own personality and core values. These reflections were then to be captured in a short personal leadership statement. Include this leadership statement in your blog entry for this week, answering the following:

1. What are your core leadership values?

2. What do you expect of the people you work with?

3. What can the people you work with expect from you?

4. How will you evaluate your performance?

In what situations do I seek to confirm my biases rather than control them? In what situations do I interpret evidence in a way that flatters my bias?

1. Calculate the NET VO2 for someone walking on a treadmill at 3.5 mph and a 12% grade.

What is 80% of this person's VO2reserve?

2. What is the predicted VO2 for 62 kg man cycling at a resistance of 147 watts. You must show all your work for full credit.

3. Why do exercise scientist have objective criteria to see whether a true VO2 max was reached? List/name at least 4 of the criteria that must be met for a TRUE VO2max test. What is it called when the criteria is not met?

4.

Please give a general description of the differences between two component models vs. multi-component models for estimating body composition. Ex: what components do they look at? Is one preferred over the other? Why should we care about the components that are being measured?