Question

Q. 1a): Name five vehicles used in oral solutions.

b): Name five important physiochemical properties to be considered while preparing oral liquids.

c): Give five important characteristics of vehicle used in oral liquids.

Answer 1

Answer: Five vehicles used in oral solutions and their characteristics are:

1) Water–has the widest range of usefulness of all the solvents employed in pharmaceutical dispensing or manufacturing. It is a good solvent for most inorganic and organic.

2) Alcohol USP, Ethyl Alcohol, Ethanol–good solvent for many organic substances both natural and synthetic. Is 94.9 to 96.0% alcohol at 15.560C.

3) Glycerin USP ( Glycerol)–clear syrupy liquid with sweet taste. It is miscible both with water and alcohol. Excellent solvent for tannins, phenol and boric acid. It has a preservative qualities.

4) Chloroform–miscible with alcohol, ether, benzene, hexane and both fixed and volatile oils.

5) Polyethylene glycol 400–miscible in water, acetone alcohol and other glycols.

Answer: Liquid form of a dose of a drug used as a drug or medication intended for administration or consumption. For the preparation of oral liquids many its physiochemical properties should be considered as:

It should not be volatile.

It should not be reactive with other ingredients.

It should be easily dissolved .

Have better shelf life.

Advantages:

• Faster absorption than solids

• Palatable pleasant to taste

• Best choice for children and old persons