Question

In: Nursing

Which factor is more than likely the reason for the rapid speed of action of injected...

Which factor is more than likely the reason for the rapid speed of action of injected drugs?

Question 16 options:

1)

How quickly the substance enters the bloodstream

2)

How quickly it reaches the site of action

3)

How much of the drug reaches the target site

4)

All of the above

Question 17 (1 point)
A new drug is being developed to treat acne. Scientists have found that a therapeutic does is about 150mg, and that an increase of 5mg is sufficient to cause bizarre skin rashes. This new drug has narrow:

Question 17 options:

1)

Site of action

2)

Potency to toxicity ratio

3)

Margin of safety

4)

Dose-response curve

Question 18 (1 point)
When a person is given a dose of 2mg of Ativan, it takes approximately 6 hours for 1mg of Ativan to leave the body. This refers to Ativan's

Question 18 options:

1)

Time to biotransformation

2)

Plateau effect

3)

Rate of metabolism

4)

Half life

Question 19 (1 point)
Gene has cirrhosis and when he takes Tylenol, he has a much different response to it than his wife. Which of the following is the most likely contributing factor to this difference in response?

Question 19 options:

1)

Body size

2)

Stomach contents

3)

Liver enzyme activity

4)

Health status

Expert Solution

16 .ANSWER IS 1

1) how quickly the substance enters the blood stream

injection is the act of putting a liquid, especially a drug, into a persons body using a needle (ususally a hypodermic needle) and a syringe. although there are various method of taking drugs, injection is favoured by some people as the full effects of the drug are experienced very quickly , typically in five to ten ten seconds. if the drug reaches the blood ,the action starts rapidly. hence effect of drug is achieved by the patient

17.ANSWER IS 2

2) Potency to toxicity ratio

Drug toxicity refers to the adverse or lethal reaction to an administered dose of a medication.Potency is a word that efers to the relative dose that is necessary to produce a drug effect of a defined magnitude

Site of action- drugs act on the cell membrane by physical or chemical interactions .this is usually through specific drug receptor sites known to be located on the membrane .A receptor is the specific chemical constituents of the cell with which adrug interacts to produce its pharmacological effects

Margin of safety- it is the difference between the intrinsic value of a stock and its market price

Dose response curve-

dose is the amount of drug to administered to producce a certain degee of response in a patient

response is the change inactivity of the cell or tissue produce by the selected dose of the drug

a typical curve showing the dose response relationship is called dose response curve

18) ANSWER is 4

4) Half life- the elimination half life of a drug is a pharmacokinetic parameter that is defined as the time it takes for the concentration of the drug in the plasma or taotalamount in the body to be reduced by 50%.in other words after one half life , the concentration of the drug in the body wil be half of the starting dose

time to biotransformation - it is the process by which a substance changes from one chemical to another ( transformed ) by a chemical reaction within the body

plateau effect- most drugs are eliminated from the blood plasma with first order kinetics .

rate of metabolism- it is the rate of metabolism , the amount of energy used by an animal per unit of time

19 ) ANSWER IS 3

3) Liver enzyme activity

since the Gene has cirrhosis , there willbe fibrous tissue formationin the liver. so the live cannot metabolise the drug.the function of liver is also disturbed .so he may have less effect of tylenol when compared t o his wife

Nightingale answered 2 years ago

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