Question
In: Statistics and Probability
5. A randomized controlled trial is run to evaluate the effectiveness of a new drug for...
5. A randomized controlled trial is run to evaluate the effectiveness of a new drug for asthma in children. A total of 250 children are randomized to either the new drug or placebo (125 per group). The mean age of children assigned to the new drug is 12.4 with a standard deviation of 3.6 years. The mean age of children assigned to the placebo is 13.1 with a standard deviation of 4.0 years. Is there a statistically significant difference in ages of children assigned to the treatments? Run the appropriate test at a 5% level of significance. Please use the five steps and explain the meaning of the results.
Solutions
orchestra answered 2 years agoRelated Solutions
STATS A randomized trial was performed to evaluate the effectiveness of a new drug on controlling...
STATS
A randomized trial was performed to evaluate the effectiveness
of a new drug on controlling Type I diabetes in teenagers. A random
sample of 150 patients were obtained from the pediatric diabetes
clinic at Sick Kids in Toronto, Ontario; 75 were randomly assigned
to the treatment group (new drug) and 75 were randomly assigned to
the control group (existing drug). You may assume that basic
factors such as validity of the inclusion criteria, blinding, etc.
were performed appropriately.Baseline information...
A randomized trial was performed to evaluate the effectiveness of a new drug on controlling Type...
A randomized trial was performed to evaluate the effectiveness
of a new drug on controlling Type I diabetes in teenagers. A random
sample of 100 patients were obtained from the pediatric diabetes
clinic at Sick Kids in Toronto, Ontario; 50 were randomly
assigned to the treatment group (new drug) and 50 were randomly
assigned to the control group (existing drug). You may
assume that basic factors such as validity of the inclusion
criteria, blinding, etc. were performed appropriately. Baseline
information...
A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm...
A clinical trial is run to investigate the effectiveness of an
experimental drug in reducing preterm delivery to a drug considered
standard care and to placebo. Pregnant women are enrolled and
randomly assigned to receive either the experimental drug, the
standard drug or placebo. Women are followed through delivery and
classified as delivering preterm (< 37 weeks) or not. The data
are shown below.
Preterm Delivery
Experimental Drug
Standard Drug
Placebo
Yes
20
32
36
No
80
68
64
a)...
A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm...
A clinical trial is run to investigate the effectiveness of an
experimental drug in reducing preterm delivery to a drug considered
standard care and to a placebo. Pregnant women are enrolled and
randomly assigned to receive either the experimental drug, the
standard drug, or a placebo. Women are followed through delivery
and classified as delivering preterm (< 37 weeks) or not. The
data are shown below. Using this data, conduct the appropriate
hypothesis test to assess if there a statistically...
A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm...
A clinical trial is run to investigate the effectiveness of an
experimental drug in reducing preterm delivery.
Preterm delivery Experimental Drug Standard Drug Placebo
Yes 17 23 35
No 83 77 65
a) what test statistic is used to compute?
b) what is the critical value for the test
Q3. A clinical trial is run to investigate the effectiveness of an experimental drug in reducing...
Q3. A clinical trial is run to investigate the effectiveness of
an experimental drug in reducing pre-term delivery to a drug
considered standard care and to placebo. Pregnant women are
enrolled and randomly assigned to receive either the experimental
drug, the standard drug, or placebo. Women are followed through
delivery and classified as delivering pre-term (< 37 weeks) or
not. The data are shown below.
Pre-term Delivery
Experimental Drug
Standard Drug
Placebo
Yes
20
32
36
No
80
68
64...
A clinical trial is run to investigate the effectiveness of an experimental drug in reducing preterm...
A clinical trial is run to investigate the effectiveness of an
experimental drug in reducing preterm delivery to a drug considered
standard care and to a placebo. Pregnant women are enrolled and
randomly assigned to receive either the experimental drug, the
standard drug or a placebo. Women are followed through delivery and
classified as delivering preterm (< 37 weeks) or not. The data
are shown below.
Preterm Delivery
Experimental Drug
Standard Drug
Placebo
Yes
17
23
35
No
83
77...
A randomised controlled trial was conducted to assess the effectiveness of a new eye drop to...
A randomised controlled trial was conducted to assess the
effectiveness of a new eye drop to reduce eye pain in patients
suffering from a systemic condition affecting both eyes. Each
patient received the prescribed dose of the new eye drop in one eye
and the same dose of an existing drop in the other eye. The
investigators randomised which eye was treated with the new eye
drop and which received the existing eye drop. 45 patients were
asked to rate...
A randomized experimental study was conducted to evaluate the effectiveness of a new cancer vaccine. One-thousand...
A randomized experimental study was conducted to evaluate the
effectiveness of a new cancer vaccine. One-thousand healthy adults
were randomized to receive either the new vaccine (500 adults) or
the old vaccine (500 adults). The adults were followed for 10 years
to monitor the incidence of colon cancer. At the end of the study,
the risk ratio for developing colon cancer was 0.5 among the adults
who received the new vaccine compared to adults who received the
old vaccine. The...
A study of randomized controlled trial of animals facilitated therapy with dolphins in the treatment of...
A study of randomized controlled trial of animals facilitated
therapy with dolphins in the treatment of (mild and moderate)
depression collected the data as follows:
Depression Improved
Treatment
Yes
No
Total
Dolphin
10
5
15
Control
3
12
15
Total
13
17
30
Is the distribution of patients' depression significantly
different between dolphin treatment and control treatment? Is there
a treatment effect or could such a difference be explained by
chance? Use the 8 step procedure to answer this
question.
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