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In: Chemistry

Contrast the structure of SINE and LINE DNA sequences. Why are LINEs referred to as retrotransposons?...

Contrast the structure of SINE and LINE DNA sequences.

Why are LINEs referred to as retrotransposons?

Use the terms in bold to fill the appropriate blanks to complete the sentences.

they contain genes for transposition

100,000

unique

about 6 kb

repetitive

1,500,000

their mechanism of transposition resembles that used by retroviruses

less than 500 base pairs long

Long interspersed elements (LINEs) are ________ transposable DNA sequences in humans. The most prominent family, designated L1, is ________ each and is represented about ________ times. LINEs are often referred to as retrotransposons because ___________ .

Solutions

Expert Solution

Long interspersed elements (LINEs) are _ repetitive transposable DNA sequences in humans

The most prominent family, designated L1, is _ about 6 kb each and is represented about _ 100,000 times.

LINEs are often referred to as retrotransposons because _ their mechanism of transposition resembles that used by retroviruses

Short Interspersed Nuclear Elements are short DNA groupings (<500 bases) that speak to switch deciphered RNA atoms initially interpreted by RNA polymerase III into exchange RNA, 5S ribosomal RNA, and other little atomic RNAs. The system of retrotransposition of these components is more entangled than LINEs, and less reliant exclusively on the real components that they encode. SINEs don't encode a practical turn around transcriptase protein and depend on other portable components for transposition. Now and again they may have their own particular endonuclease that will permit them to cut their way into the genome, however the lion's share of SINEs incorporate at chromosomal breaks by utilizing arbitrary DNA breaks to prime invert transcriptase. With around 1,500,000 duplicates, SINEs make up around 11% of the human genome

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Contrast the structure of SINE and LINE DNA sequences.

Since quite a while ago scattered components (LINEs) are a gathering of non-LTR (long terminal rehash) retrotransposons which are far reaching in the genome of numerous eukaryotes. They make up around 20% of the human genome. A few sources additionally give "Since quite a while ago scattered atomic component" as the long shape for LINE. LINE remains for Long Interspersed Nuclear Elements. LINEs make up a group of transposons, where every LINE is around 7000 base matches long. LINEs are interpreted into mRNA and converted into protein that goes about as a turn around transcriptase. The invert transcriptase makes a DNA duplicate of the LINE RNA that can be incorporated into the genome at another site. There are around 100,000 LINEs in your genome. Because of the collection of arbitrary transformations, the grouping of many LINES has deteriorated to the degree that they are did not interpret anymore or deciphered. Correlations of LINE DNA groupings can be utilized to date transposon inclusion in the genome.

Why are LINEs referred to as retrotransposons?

Retrotransposons (additionally called transposons by means of RNA intermediates) are hereditary components that can open up themselves in a genome and are omnipresent segments of the DNA of numerous eukaryotic living beings. They are one of the two subclasses of transposon, where the other is DNA transposon, which does not include a RNA middle of the road. They are especially copious in plants, where they are regularly an important part of atomic DNA.

Since a long time ago scattered components (LINEs) are a gathering of non-LTR (long terminal rehash) retrotransposons which are across the board in the genome of numerous eukaryotes. They make up around 20% of the human genome. A few sources additionally give "Since quite a while ago blended atomic component" as the long frame for LINE. LINE remains for Long Interspersed Nuclear Elements. LINEs make up a group of transposons, where every LINE is around 7000 base matches long. LINEs are deciphered into mRNA and converted into protein that goes about as a turn around transcriptase. The invert transcriptase makes a DNA duplicate of the LINE RNA that can be coordinated into the genome at another site. There are around 100,000 LINEs in genome.


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