In: Biology
describe 2 different inductive factors which play a role in the PNS. which inductive factors derived from glial cells?
Bilaterians are having two Central Nervous System (CNS) and Peripheral Nervous System (PNS) wherein PNS is made up of nerves and ganglia. The cells of PNS are having several growth factors will control the expression of genes under normal condition as well as in an altered situation like injuries through replacement of malfunctioned cells by apoptosis followed by regeneration. Among them nerve growth factor (NGF) and they further subdivided in to different category, this factor is principle inductive factor of PNS and play role in differentiation and its survival. This factor is responsible for induction of signal transduction proteins like ERK and JNK. Another inductive factor is fibroblast growth factor (FGF-2) for development, regeneration and proliferation of cells of PNS.
Signal in Glial cell activated and regulated by an inductive factors, which is also know as transcription factor TGF β-1 (Transforming growth factor) that encode several molecules against any stimuli like immune response and faciliated by cytokines like interleukins.