Question

1. In your own words, describe the effects of MDMA in PNS and CNS.

2. What are some of the contaminants often found in MDMA or Molly?

3. What three neurotransmitters are affected by MDMA, and in what way? (be specific for each one)

4. Regular use of MDMA will cause what? Why does this occur?

Answer 1

Ans 1:

• MDMA is Methylenedioxymethamphetamine.
• Effects of MDMA in PNS includes:

(i) Immunosuppressive effects

(ii) Increase in heart rate

(iiI) Increase in Blood pressure and

(iv) Increase in anxiety.

• Effects of MDMA in CNS includes:

(i) Drug of abuse

(ii) Increased secretion and decrease in reuptake of serotonin, dopamine and noradrenaline in the brain.

(iiI) Increase in behavioural effects like euphoria, emotional openness etc.

Ans 2: Contaminants found in MDMA or Molly as adulterants generally includes:

(i) para-Methoxyamphetamine (PMA)

(ii) Ketamine

(iii) Caeffine

(iv) Ephedrine

(v) Dextromethorphan

Ans 3: MDMA is responsible for the stimulation in the levels of three neurotransmitters i.e. Dopamine, Serotonin (5-HT) and Noradrenaline (Norepinephrine) by making an interaction with their respective transporter proteins, which thereby resulting in the release and increase in the neurotransmitter activity in the brain.

Ans 4: Regular use of MDMA can cause various unwanted effects that includes:

(i) Depression

(ii) Disturbances in Sleep activity

(iii) Loss of appetite

(iv) Confusion

(v) Memory Loss and many other effects also.