In: Biology
explain how the simple gradient of bicoid can give rise to the pattern of even-skipped gene
The gradient of bicoid can give rise to the pattern of the even-skipped gene:
Bicoid genes are present on the anterior side of the Drosophila embryo. Bicoid protein is responsible for making the anterior structures in Drosophila. Bicoid genes are maternal effect genes whereas even-skipped genes are the example of primary pair-rule genes. Initially, in embryo, maternal effect genes are responsible to carry out the processes but after mid blastula stage, these maternal effect genes (for example bicoid, Nanos, caudal) act as a transcription factor(TF) and bring about the expression of Zygotic genes like gap genes, pair-rule genes, segment polarity genes, homeotic genes, and realisator genes. The expression of these genes occurs in the same sequence as they are written. The product of maternal genes regulate the expression of gap genes, gap genes product regulates the pair-rule gene and further pair-rule gene product regulates the segment polarity gene. the product of these 3 genes helps in the expression of Homeotic genes that further regulate expression of realisator genes.