In: Biology
Two ribosomal subunits have sedimentation coefficients of 60S and 40S. Assuming that both subunits have spherical shapes and their densities are equal, calculate the ratio of their molecular weights ( not with the actual molecular weight values).
The sedimentation coefficients are 60 S & 40 S
both subunits have spherical shapes & their densities are equal
1 Swedberg unit= 10-13
Two ribosomal subunits have Sedimentation coefficient =
Large subunit= 60 S
= 60 X 10-13
small subunit = 40S
= 40 X 10-13
molecular mass of 60 S subunit is = 3 million gram /mole
& 40S subunit = 1.5 million gm /mole
ratio of their molecular weight = large subunit / small subunit
= 3 /1.5
= 1.5 million gram /mole