Question

In: Biology

Two ribosomal subunits have sedimentation coefficients of 60S and 40S.

Two ribosomal subunits have sedimentation coefficients of 60S and 40S. Assuming that both subunits have spherical shapes and their densities are equal, calculate the ratio of their molecular weights ( not with the actual molecular weight values).

Solutions

Expert Solution

The sedimentation coefficients are 60 S & 40 S

both subunits have spherical shapes & their densities are equal

1 Swedberg unit= 10-13

Two ribosomal subunits have Sedimentation coefficient =

Large subunit= 60 S

= 60 X 10-13

small subunit = 40S

   = 40 X 10-13

molecular mass of 60 S subunit is = 3 million gram /mole

& 40S subunit = 1.5 million gm /mole

ratio of their molecular weight = large subunit / small subunit

   = 3 /1.5

   = 1.5 million gram /mole

     


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