In: Nursing
Blood Group System |
Rh |
Kell |
Kidd |
Duffy |
MNSs |
Lewis |
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What are the major antigens |
(5): D C, c, E, e |
(2) K and k |
(2) |
(2) |
(4) |
(2) |
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Do the agn/aby reactions demonstrate dosage? |
Yes, all except D |
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Low frequency agns High frequency agns |
e D, C, c, E |
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Cause Transfusion Reactions? If yes, are they Intra- or extravascular? If yes, are they immediate or delayed? |
Yes Extravascular delayed |
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Abys are IgM or IgG? |
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Abys cause Hemolytic Disease of Fetus/Newborn? |
Yes |
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Abys bind Complement? |
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Best reaction condition |
37 and IAT |
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What stimulates antibody production? |
Transfusion or pregnancy |
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Other |
Rh null = ---/--- |
fill the blank of the table Rh, Kell, Kidd, Duffy, MNSs, Lewis
Rh | Kell | Kidd | Duffy | MNSs | Lewis | |
Blood Group System what are the major antigen? | D,C,E,c and e |
2 K,k |
3 Jk1(Jka), Jk2(Jkb),Jk3 |
6 Fya,Fyb,Fy3 ,Fy4,Fy5,Fy6 |
42 M,N,S,s |
2 Le-a, Le-b |
Do the agn/ aby reactions demonstrate dosage? |
yes, all except D | yes, K | Yes, Jk1, Jk2 | Yes | yes | No |
Low frequency agns | e | K | Jka,jkb | Fy4, Fy5, Fy6 | ............... | ............. |
High frequency agns | D, C,c,E | k | Jk3 | Fy3,Fyb, Fya | M,N,S,s | Le-a, Le-b |
Cause Transfution Reaction? If yes ,are they Intra-or extravascular? If yes, are they immediate or delayed? |
Yes Extravascular delayed |
Yes Extravascular immediate |
Yes Intravascular delayed |
Yes extravascular delayed |
Uncommon |
No |
Abys are IgM or IgG? | Mainly IgG | IgG | IgG | IgG | depend upon which antigen is targeted. | IgM |
Abys cause Hemolytic Disease of Fetus/ Newborn ? Abys bind Complement? |
Yes |
Yes No |
Yes Yes |
Yes No |
uncommon |
No no |
Best reaction condition | 37 and IAT | |||||
What stimulates antibody production? | Transfusion or pregnancy | pregnancy | Pregnancy | Pregnancy, Asthma, Makaria, HIV infection |
Transfution |
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Other | Rh null | Kell null | Jknull | ...... | other 41 antigen in MNS group |