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In: Nursing

Blood Group System Rh Kell Kidd Duffy MNSs Lewis What are the major antigens (5): D...

Blood Group System

Rh

Kell

Kidd

Duffy

MNSs

Lewis

What are the major antigens

(5): D C, c, E, e

(2) K and k

(2)

(2)

(4)

(2)

Do the agn/aby reactions demonstrate dosage?

Yes, all except D

Low frequency agns

High frequency agns

e

D, C, c, E

Cause Transfusion Reactions?

If yes, are they Intra- or extravascular?

If yes, are they immediate or delayed?

Yes

Extravascular

delayed

Abys are IgM or IgG?

Abys cause Hemolytic Disease of Fetus/Newborn?

Yes

Abys bind Complement?

Best reaction condition

37 and IAT

What stimulates antibody production?

Transfusion or pregnancy

Other

Rh null =

---/---

fill the blank of the table Rh, Kell, Kidd, Duffy, MNSs, Lewis

Solutions

Expert Solution

Rh Kell Kidd Duffy MNSs Lewis
Blood Group System what are the major antigen? D,C,E,c and e

2

K,k

3

Jk1(Jka), Jk2(Jkb),Jk3

6

Fya,Fyb,Fy3

,Fy4,Fy5,Fy6

42

M,N,S,s

2

Le-a, Le-b

Do the agn/ aby reactions demonstrate dosage?

yes, all except D yes, K Yes, Jk1, Jk2 Yes yes No
Low frequency agns e K Jka,jkb Fy4, Fy5, Fy6 ............... .............
High frequency agns D, C,c,E k Jk3 Fy3,Fyb, Fya M,N,S,s Le-a, Le-b

Cause Transfution Reaction?

If yes ,are they Intra-or extravascular?

If yes, are they immediate or delayed?

Yes

Extravascular

delayed

Yes

Extravascular

immediate

Yes

Intravascular

delayed

Yes

extravascular

delayed

Uncommon

No
Abys are IgM or IgG? Mainly IgG IgG IgG IgG depend upon which antigen is targeted. IgM

Abys cause Hemolytic Disease of Fetus/ Newborn ?

Abys bind Complement?

Yes

Yes

No

Yes

Yes

Yes

No

uncommon

No

no

Best reaction condition 37 and IAT
What stimulates antibody production? Transfusion or pregnancy pregnancy Pregnancy Pregnancy, Asthma, Makaria, HIV infection

Transfution

Other Rh null Kell null Jknull ...... other 41 antigen in MNS group

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