(DRUG DOSAGE PROBLEM) A drug company wants to know how to calculate a suitable dose and time...

(DRUG DOSAGE PROBLEM) A drug company wants to know how to calculate a suitable dose and time between doses to maintain a safe but effective concentration of a drug in the blood. To be simple for the users of the drug, only a fixed dose at regular time intervals is considered possible. Suggest a way to model the problem, determine the main issues involved, and work out a solution. The answer should be a formula or algorithm for computing the dose and time interval.

It is up to you to make the problem formulation precise, to determine what additional input data you might need, to make necessary reasonable assumptions and simplifications, and to decide how to organize your work in suitable subtasks. Hint: Do not mix all difficulties at the same time. First think just on a suitable model rather than trying to solve the problem. Only consider the most basic aspects first, and make appropriate simplifications. The model can be extended later if this is needed.

Expert Solution

Colby Messinger answered 2 years ago

A researcher wants to investigate the bioactivity of a new drug. Dosage Observations

A researcher wants to investigate the bioactivity of a new drug. Dosage Observations 20g 26 28 37 30 30g 427 49 36 405 40g 42 47 52 38 Conduct a one-way ANOVA by hand and provide the ANOVA table. Use alpha=0.05. Please show your work clearly. Provide Tukey’s HSD test for multiple comparison by hand. Use alpha=0.05.

20. Calculate the total dose in cubic centimeters of a drug, to be administered SQ to...

20. Calculate the total dose in cubic centimeters of a drug, to be administered SQ to a patient weighing 12 pounds. The concentration of the drug is 2mg/ml and the dosage rate is 10mg per kg._____________ 21. Calculate the total dose in cubic centimeters of a drug, to be administered SQ to a patient weighing 105 pounds. The concentration of the drug is 100mg/ml and the dosage rate is 15mg per kg._____________

19. Calculate the total dose in cubic centimeters of a drug, to be administered IV to...

19. Calculate the total dose in cubic centimeters of a drug, to be administered IV to a patient weighing 81 pounds. The concentration of the drug is 20mg/ml and the dosage rate is 11mg per kg._____________ A. Calculate the total dose in cubic centimeters of a drug, to be administered SQ to a patient weighing 17 pounds. The concentration of the drug is 2mg/ml and the dosage rate is 10mg per kg._____________ B. Calculate the total dose in cubic centimeters...

The logistics company wants to know if the time it takes to receive shipments is the...

The logistics company wants to know if the time it takes to receive shipments is the same or different for two shipping companies. A random sample of delivery times is selected for each of the two shipping firms. The null and alternative hypotheses are: ?0: (?1−?2)=0 ??: (?1−?2)≠0 A 0.10 significance level is chosen for this two-tailed test. The samples are selected, and the results are: ?1 = 14.8 ???? ?1 = 4.6 ???? ?1 = 35 ?2 = 17.4...

head of department in any company wants to know the relationship between drug abuse and dysfunctional...

head of department in any company wants to know the relationship between drug abuse and dysfunctional behavior with in organization.. so what will be relevent population for research?, approprite sample design? and appropriate sample size.? business reseach method ( short ans please)

Consider a problem in pharmacokinetics concerned with the dose-response relationship of a drug with its rate...

Consider a problem in pharmacokinetics concerned with the dose-response relationship of a drug with its rate of clearance λC^2 , where C(t) denotes the concentration of the drug in a patient ’s body at time t. Let C_0 be the concentration at time t = 0, then dC / dt = −λC^2 . (1) Now suppose constant doses C_0 are given at equal intervals of time T. (a) Find the amount of drug in the body immedately after the n...

Pepto- Bismol How the drug is supplied and given (dosage form, strength, frequency, and ROA), how...

Pepto- Bismol How the drug is supplied and given (dosage form, strength, frequency, and ROA), how the drug works (MOA). Then, describe the possible side effects with corresponding warning labels. Speak of adverse reactions and any special considerations while taking this medication. Do you have it in your medicine cabinet? Why?

Drug Dosage Problem A patient takes a 30-mg (milligram) antibiotic capsule every hour. At the end...

Drug Dosage Problem A patient takes a 30-mg (milligram) antibiotic capsule every hour. At the end of any one hour, the amount of antibiotic remaining in her body is only 90% of the amount at the beginning of that hour. Your objective is to predict the total amount in her body after many hours. 1. The first 30 mg dose is taken at time t=0 h. How much of this dose remains at the end of 1 h? 2 h? ...

With repeated dosage of a drug how long in half-lives, when the plasma concentration to reach...

With repeated dosage of a drug how long in half-lives, when the plasma concentration to reach 95% of the steady state level if the drug shows a non-saturating first-order kinetics? Please calculate the number of half life and show the calculation procedure. It should be a specific number but not a range.

The director of research and development is testing a new drug. She wants to know if...

The director of research and development is testing a new drug. She wants to know if there is evidence at the 0.02 level that the drug stays in the system for more than 321 minutes. After performing a hypothesis test, she decides to reject the null hypothesis. What is the conclusion? There is sufficient evidence at the 0.02 level of significance that the drug stays in the system for more than 321 minutes. There is not sufficient evidence at the...

Question