How would a planar molecule inhibit DNA replication and an unprocessed mRNA ?

Solutions

Expert Solution

Solution:

A molecule is planar when all its atom are at the same plane.

The planar molecule acts as an intercalating agent and prevents replication and transcription. It slips between layers of nucleic acid pairs and disrupts the shape of helix which affects DNA replication and mRNA transcription.

During Replication of DNA, DNA is uncoiled by helicase enzyme. This causes tension in the DNA which is relieved by topoisomerase II enzyme.

Planar molecule also causes inhibition of topoisomerase II. The role of this enzyme is to relieve the strain of DNA by cleaving the DNA chain so that both the strands can pass through each other But due to planar molecule, this tension is not resolved hence causing inhibition of DNA replication.

In mRNA transcription the double stranded DNA needs to separate so that DNA sequence can be copied. But due to inhibition of topoisomerase II the strain in DNA is not resolved which also affects mRNA transcription.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Diagram (draw) and describe the process of DNA replication. Include original molecule, the DNA molecule unzipping,...

Diagram (draw) and describe the process of DNA replication. Include original molecule, the DNA molecule unzipping, the addition of new nucleotides, and the products of replication.

During cell division, DNA undergoes replication. DNA is transcribed into mRNA and the genetic code is...

During cell division, DNA undergoes replication. DNA is transcribed into mRNA and the genetic code is translated into a polypeptide sequence. Out of these three processes, which is most likely to be the site a deletion, frameshift, insertion missense, nonsense, point and silent mutation or alteration occurred? Explain why you have chosen this process. 15 marks

What features of DNA replication cause each new DNA molecule to be exactly like the original?...

What features of DNA replication cause each new DNA molecule to be exactly like the original? (1pt) C. Why is replication an important cell process? (1pt) Point Mutation A. How does the point mutation that you made change the DNA code on your molecule? (2pts) B. Referring to your textbook, explain how mutations can occur in cells and how such changes might affect an organism with the mutation. (2pts)

DNA replication is a [1] process because each new molecule has [2] strand of [3] DNA...

DNA replication is a [1] process because each new molecule has [2] strand of [3] DNA and [4] of [5] DNA. The role of [6] is to unzip the double helix. DNA polymerase extends the [7] primers made by the primase. On the [8] strand the DNA synthesis is discontinuous, on the [9] strand is instead continuous. The reason for this difference is that [10]. Please fill in the numbered blanks and for the [10] can you make a sentence...

DNA replication

1-what seniconsevative replication is and how it was discovered to be the corrext model DNA replication....

1-what seniconsevative replication is and how it was discovered to be the corrext model DNA replication. 2-List the eays tgat chromatin remodeling xomplexes can remodel de DNA and what are their functions? 3-how interphase chrimarin isnorganized in the nucleous and how it is condensed to regulate expression.

Explain what would happen during DNA replication if both DNA Pol I and DNA Pol III...

Explain what would happen during DNA replication if both DNA Pol I and DNA Pol III had high processivity. in writing no diagrams or pictures

How semi conservative DNA replication prevent mutation? why semi-conservative dna replication is more important than conservative...

How semi conservative DNA replication prevent mutation? why semi-conservative dna replication is more important than conservative replication? thank you

1. The use of RNA primer in DNA replication increases the fidelity of DNA replication. Explain...

1. The use of RNA primer in DNA replication increases the fidelity of DNA replication. Explain this statement. 2. Some errors in DNA replication can escape repair and this is to some extent is beneficial for the evolution. Explain why?

Describe the process of DNA replication

Subjects