Question

In: Biology

1. The adaptive immune system can differentiate own and foreign antigens because? Lymphocytes react with self-antigens...

1. The adaptive immune system can differentiate own and foreign antigens because?

Lymphocytes react with self-antigens are deleted during fetal development.

Lymphocytes react to self-antigens, which do not generate an immune response.

All lymphocytes have no capacity to bind self-antigens.       
Innate immune response only works against foreign antigens.

2. During neuron differentiation and synapse formation, the following occurs EXCEPT?

Radial glial cells act as guide wires for migration of neuron progenitor cells.

Neurotrophic factors provide cues for migration and synapse formation.

Neuron death is normal and necessary.
Once formed during fetal development, synapses between neurons become permanent and are not easy to change.

3. During the early embryonic development, the primary function of notochord includes?

Secretion of morphogens which guide the orientation and symmetric development of embryo.
Provision of progenitor cells for the development of somites.
It becomes neural tube and, then forms the central nervous system       
It develops into connective tissues during the fetal stage.

Solutions

Expert Solution

1. Answer- Lymphocytes react to self-antigens, which do not generate an immune response.

Explanation- Adaptive immunity also called as acquired immunity are activated by exposure to pathogens and uses an immunological memory to learn about the threat and thereby enhance the immune system accordingly. Lymphocytes like B cell and T cell palys the major role.

Lymphocytes react to self-antigens, which do not generate an immune response. For instance, T cell recognizes only foreign antigens combined with self-MHC molecules for approximate immune response.For this to happen, T cells under go positive and negetive selection processes after maturation. Positive selection usually ensure the MHC restriction by testing the ability of MHC I and MHC II to distinguish between self and nonself proteins while in negetive selection process test for binding capabilities of CD4 and CD8 specifically.

Hope this helps you. Thankyou!?


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