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In: Biology

In 2004, Israel switched from using OPV to using IPV. Then, after wild-type polio was found...

In 2004, Israel switched from using OPV to using IPV. Then, after wild-type polio was found to be circulating in the population in 2013, a supplementary OPV program was begun for children who had received only IPV. Describe what would be the best rationale for an OPV supplementary program?

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Expert Solution

OPV contains all three poliovirus serotypes(1,2 and3)and the use of this vaccines has led to eradication of wild-polio virus type2(WPV2),with the last case occurring in 1922.

Oral polio Vaccine(OPV)has been effective in helping us to get closer to the Global eradication of poliovirus.These unnecessary case of WPV2 could be avoided by using Inactivated polio vaccine(IPV)instead of OPV.Hence OPV was switched to IPV.Here OPV is taken orally as drops and can be easily administered.It doesn't require a trained health worker.But OPV is still the main preventive measure taken against polio virus.

The introduction of ipv reduces risks associated with the withdrawal for OPV.It facilitate interruption of transmission with the use of monovalent OPV type 2,in the cases of outbreak.

Given the risk,the type 2 component of OPV poses to the world free of WPV2,OPV was replaced with bOPV in routine programs and supplementary immunization activities(SIAs).

The supplementary immunization programs such as mass immunization campaign are one of the four pillars of eradication.It tend to complement-not replace-routine immunization..


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