Question

research about Fungal infection common in Oman and its emergence
The research report will include the following information about Fungal infection
a.MOT( mode of transmission)
b.CA (causative agent)
c.signs and symptoms of infection
d.laboratory test
e.treatment or antimicrobial therapy
f. appropriate measures to prevent or control the infection.

Answer 1

Fungal infection common in Oman and it's emergence including all information is discussed below:-

Fungal infection caused by Candida auris that live on the skin and inside the human body C.auris can cause serious infection, people who carry the fungus that can cause serious infection. Infection caused by C.auris are comncerning because they can be more difficult to treat than other Candida infection, as they are often resistant to medicines. Mode of transmission in Candida auris can be direct contact from person to person or can be indirect contact via shared objects. For this region's C.auris can cause problems in hospitals and nursing homes.

In healthy people, C. auris colonization doesn't generally cause ill health. People may carry C.auris on their skin without any symptoms. However, this individuals are at risk of getting C.auris infection if they are hospitalised for another reason, or put on antibiotics. In some people, such as those whose immune systems is weak or compromised or who are already unwell with other conditions, C.auris can become a serious problem as it can cause serious bloodstream, wound or ear infection. Signs and symptoms include fever, chills while on antimicrobial medication, sepsis, coma, organ failure

C.auris isolated from any body site for example, urine, blood, ear, wound, skin etc must be submitted to the MDH-PHL, along with any anti-fungal susceptibility testing performed. C.auris can be misidentified with the phenotypic methods for yeast identification used by most clinical laboratory test.

C.auris infections are treatable with certain anti-fungal drugs for example, echinocandins. However, the drugs of choice depends on which drugs the fungus is susceptible. Some clinicians prefer to use more than one antifungal drug to treat these multiple drug resistant invasive organisms. C.auris is highly resistant to fluconazole followed by nystatin. As expected control strain of C.albicans SC5314 was sensitive to all the four antifungal agents. MIC results of all the tested compounds showed all compounds have antifungal activity against C.

Appropriate measures to prevents the C.auris infection are:- adherence to hand hygiene, transmission based precautions based on settings, cleaning and disinfecting the patient care environment, transferred to another health care facility, screening contacts of newly identified case patients to identify C.auris colonization, laboratory surveillance. ABHS is effective against C.auris.