A 72 kg patient is started on a drug with an IV bolus dose of 180...

A 72 kg patient is started on a drug with an IV bolus dose of 180 mg. After 24 hours a dose of 80 mg is given, and after another 8 hours a dose of 120 mg is given. Using the principle of superposition determine the concentration of the drug 3 hours after the second dose and 2 hours after the third dose. The drug has a half-life of 9.2 hours and a volume of distribution of 0.105 L/kg. Elimination of the drug can be explained using a one compartment model and first order elimination kinetics.

Expert Solution

Amanda K answered 5 months ago

A client who weighs 175 pounds is receiving an IV bolus dose of Heparin 80 units/kg....

A client who weighs 175 pounds is receiving an IV bolus dose of Heparin 80 units/kg. The Heparin is available in a 2mL vial, labeled 10,000 units/mL. How many mL should the nurse administer? (If rounding, round to the nearest tenth). Please show your work.

The patient has an order for a Heparin bolus of 7,000 units, followed by an IV drip of 12 units/kg/hr.

The patient has an order for a Heparin bolus of 7,000 units, followed by an IV drip of 12 units/kg/hr. The patient weighs 143 lbs. The nurse has a Heparin vial labeled 5,000 units/mL. (Round final answer to nearest tenth). How many mL will be administered for the initial bolus? ____ mL

1. A physician orders a dose of 30mg/kg of a drug in 100mL NS for an 120lb patient.

1. A physician orders a dose of 30mg/kg of a drug in 100mL NS for an 120lb patient.part A. If the drug is available at 2g/10mL, how much of the drug (in mL) should be added to the bag? Round to the nearest tenth.part B. The infusion set delivers 20 drops.ml. What is the flow rate in gets.min if the infusion is to be delivered over 1 hour? Do not include the volume of additive.2. The recommended dose of a...

19. Calculate the total dose in cubic centimeters of a drug, to be administered IV to...

19. Calculate the total dose in cubic centimeters of a drug, to be administered IV to a patient weighing 81 pounds. The concentration of the drug is 20mg/ml and the dosage rate is 11mg per kg._____________ A. Calculate the total dose in cubic centimeters of a drug, to be administered SQ to a patient weighing 17 pounds. The concentration of the drug is 2mg/ml and the dosage rate is 10mg per kg._____________ B. Calculate the total dose in cubic centimeters...

A patient is to recieve 80 units heparin bolus before an infusion is started. The heparin...

A patient is to recieve 80 units heparin bolus before an infusion is started. The heparin is available in a concentration of 1000 units/mL, how many milliters of heparin should be adminsitered ? Show work

The dose of ofatumumab (Arzerra) for a patient is 300 mg. In preparing an IV infusion,...

The dose of ofatumumab (Arzerra) for a patient is 300 mg. In preparing an IV infusion, a pharmacist draws the calculated volume of drug from a 50-mL vial containing 1 g of the drug. This quantity is then added to a 1-L bag of normal saline. The infusion is programmed to flow at a rate of drug of 3.6 mg per hour. (a) What volume (in mL) of the drug from the vial is needed for the patient's dose? (b)...

A nurse is to administer prescribed heparin of 30 units/kg IV bolus before starting the continuous...

A nurse is to administer prescribed heparin of 30 units/kg IV bolus before starting the continuous infusion. Heparin 500 units/ml is available. The client weighs 200 pounds, How many milliliter of heparin bolus should the nurse administer. answer in 2 decimal place.

A nurse is to administer prescribed heparin of 100 units/kg IV bolus before starting the heparine...

A nurse is to administer prescribed heparin of 100 units/kg IV bolus before starting the heparine normogram. The client weighs 94 kg. how many units of heparin bolus should the nurse administer. available heparine dose is 1000 units/ml.

You are to give a heparin bolus of 1000 u / kg. The patient weighs 175lbs....

You are to give a heparin bolus of 1000 u / kg. The patient weighs 175lbs. The vial of heparin is 10,000u/mL. How many mLs will you administer? You have to calculate the I & O on your patient for your twelve hour shift. Your patient has had the following. NS at 100 mL/hr IV 2 cups of coffee Â½ cup of jello 1 cup of ice cream 8oz of chicken broth Voided 650 mL Chest tube drainage 120 mL

This patient is receiving a medication for treatment of cardiac arrhythmia. An IV loading dose results...

This patient is receiving a medication for treatment of cardiac arrhythmia. An IV loading dose results in a peak serum concentration of 6.0 μg/mL. The therapeutic range for this medication is 4-8 μg/mL, and its half-life is 4 hours. Four hours after the initial loading dose, another equivalent dose was given as a bolus. This resulted in a peak serum concentration of 7.5 μg/mL. Questions: 1. Does the serum concentration after the second dose seem appropriate? If not, what would...

Question