In: Biology
The product rule in DNA type matching is important since
- it allows the determination of blood type of the suspect
- it allows for the determination of the sex of the suspect
- it allows for a better confirmation of the match between a suspect and the DNA evidence found
- it unequivocally demonstrates the population genetics of the suspect
- it determines the sequence polymorphism for a suspects DNA
The product rule in DNA type matching is important since
- it allows for a better confirmation of the match between a suspect and the DNA evidence found .
Explanation :
A typical DNA case involves the comparison of two samples – an unknown or evidence sample and a known or reference sample.
If the DNA profile obtained from the two samples are matching, that implies the samples have a common source .If the DNA profile consists of a combination of traits that figure to be extremely rare, the evidence is very strong that the suspect is the contributor. To the extent that the DNA profile is not so rare, it is easier to imagine that the suspect might be unrelated and that he matches only by chance.Therefore it is essential to have some idea as to the probability that a match would occur by chance. The application of the product rule presumes that the relevant loci and population be in Hardy-Weinberg equilibrium and linkage equilibrium.By multiplying together the frequencies of the per-locus genotypes, which is to say, by multiplying together the frequencies of all the individual alleles and including in addition a factor of 2 for each heterozygous locus. This way the frequency of a DNA profile is obtained. If the frequency of chance obtained is very less,it is very unlikely that is a chance of coincidence .