Question

List similarities and differences between kawasaki disease and covid 19. Also, list treatment and diagnosis.

Answer 1

Kawasaki disease is an illness that causes bloodvessels to become inflamed, almost always in young children. It’s one of the leading causes of heart disease in kids. Symptoms also includes a persistent high fever, bloodshot eyes, redness around the mouth, a body rash and redness and swelling of the feet and hands. As it is a rare disease, doctors still don’t know exactly what causes Kawasaki disease, but the dominant theory is that a pathogen, most likely a virus, pushes a child’s immune system into overdrive, resulting in inflammation throughout the body. But then they also came up to think like there could only be one cause or trigger for the disease and recently it's  possible that SARS-CoV-2, the virus that causes COVID-19, is one of those triggers. It is also shown that it’s possible SARS-CoV-2 affects Kawasaki-prone children differently, depending on their unique genetic blueprints. Some could clear a SARS-CoV-2 infection without any inflammatory response. Others could go on to develop Kawasaki-like illness, while still others might exhibit an inflammatory response slightly different than Kawasaki disease. The main similarity between these two diseases is that adults with serious cases of COVID-19 are also seeing extreme inflammatory responses; they just manifest differently, causing issues like respiratory distress that is both are involved with the respiratory tract illness and the difference is COVID-19 is irrespective of age but Kawasaki disease mainly shows up in usually children who are 5 or younger. In case of Kawasaki disease if it is treated fever resolves within 24 hours and full recovery occurs whereas it doesn't happens in COVID-19. When it comes to treatment, in Kawasaki disease, Intravenous immunoglobulin is the standard treatment for Kawasaki disease and is administered in high doses with marked improvement usually noted within 24 hours and in COVID-19 it is symptomatic and supportive by self distancing. In diagnosis there are many ways to diagnose the Kawasaki disease such as conjunctivitis, throat redness, dry cracked lips, red lips, and "strawberry" tongue, changes in the arms and legs, including redness, swelling, skin peelingaround the nails, and generalized peeling. In case of COVID-19, demonstration of nasopharyngeal swab and collecting blood samples are the mostly used laboratory diagnostic tests and normally we can observe many changes in patients such as fever, difficulty in breathing, cough, fatigue, loss of smell and in some cases there are no symptoms shown.