What is LTP? What are some of the presynaptic changes observed? What are some of the...

What is LTP?
What are some of the presynaptic changes observed?
What are some of the postsynaptic changes observed?
How do the AMPA and NMDA glutamate receptors contribute to LTP?

Solutions

Expert Solution

LTP mean long term Potentiation. It is the persistent strengthening of a synaptic connection. It may work for a minute or hours .It induce may due to strong tetanic stimulation to synapse. LTP is the primary mechanism of learning and memory.

Some Presynaptic change

Increase or decrease in neurotransmitter release occur during presynaptic stage.
Change in synaptic strength occur
Rapid signal at axon terminal

Some postsynaptic change

Modification in receptor or biophysical properties
Addition of AMPA channel to the synapse in large group
Change in the mode of glutamate release
AMPA channel addition to extra synaptic membrane and diffusion equilibrium of extra synaptic membrane with receptor of synapse

AMPA and NMDA are the two receptor that is important in point of view of LTP. The AMPA receptor is paired with an ion channel so that when glutamate binds to this receptor , this channel allow sodium ions to enter the post synaptic neuron.

Hope I fully explain your doubt. Thank You

gladiator answered 3 months ago

Next > < Previous

Related Solutions

1. What is LTP? Why is LTP so interesting to researchers? Describe a specific demonstration of...

1. What is LTP? Why is LTP so interesting to researchers? Describe a specific demonstration of LTP at a hippocampal site of your choice

Discuss the changes that may lead to LTP of synaptic strengthening. Focus on receptors and how...

Discuss the changes that may lead to LTP of synaptic strengthening. Focus on receptors and how they may change at the terminal button. Hint: Both Pre-synaptically and Post-synaptically. Think about how signals may be weak or strong and how they can "Cooperative" or hold "Associativity" or "Specificity". What doe these terms refer to in the neuronal signals and outcome of that activation.

You just discovered, for the first time, that LTP causes learning. Describe the molecular changes involved...

You just discovered, for the first time, that LTP causes learning. Describe the molecular changes involved in LTP. The answer should include: how AMPA and NMDA receptors are different, why this matters, how a particular protein kinase is activated, two important ways this protein kinase contributes to LTP, how a particular transcription factor is activated, how the transcription factor contributes to LTP, how retrograde messengers contribute.

Survey some of the mechanisms by which drugs can alter presynaptic and postsynaptic processes.

What are some deadlocks examples that are frequently observed on Windows and on Linux?

1. Signs that can be observed and measured and are used to quantify the changes that...

1. Signs that can be observed and measured and are used to quantify the changes that occurred due to nutrition intervention are called: A. Signs of causation B. Nutrition Care Indicators C. Nutrition Process Points D. Medical Points 2. The ___________________is a systematic problem-solving method that food and nutrition professionals use to critically evaluate nutrition-related problems and make decisions regarding them. A.Subjective, Objective, Assessment, Plan B.Medical Charting C.Nutrition Care Process 3. ___________________________is the action phase of the nutrition intervention. The...

(1) What are some of the reasons for the high levels of corporate debt observed today?...

(1) What are some of the reasons for the high levels of corporate debt observed today? (2) What is a Leveraged Buyout (LBO)? What role does debt play in an LBO? (3) Why is the current crisis particularly difficult for firms with large amounts of debt?

A production company has observed that there are changes in revenue every time it tries to...

A production company has observed that there are changes in revenue every time it tries to manipulate the price. The concerns of management were brought to your attention needing your expertise advice on how price influences quantity and subsequently revenue. The market survey revealed that the quantity demanded of the product follows a Cobb-Douglas function as presented below: Q"dx"= αP"x^β"+ε^u ........... of the form Q=AL^αK^β (Cobb Douglas production fuction) Where Qdx is the quantity demanded of commodity X and Px...

Explain the changes observed in the risk of investments when an investor increases the number of...

Explain the changes observed in the risk of investments when an investor increases the number of stocks in his or her portfolio.

What are some of the major changes in the market for physicians’ services that are affecting...

What are some of the major changes in the market for physicians’ services that are affecting both physician incomes and their practices? What measure is commonly used to indicate a shortage?

Subjects