Question

In: Biology

The oxidation of Succinate to Fumarate produces: a. the same amount ATP as the oxidation of...

The oxidation of Succinate to Fumarate produces:

a. the same amount ATP as the oxidation of Malate to Oxaloacetate.

b. more ATP than the oxidation of Malate to Oxaloacetate.

c. no ATP at all but requires the activation through ATP hydrolysis.

d. less ATP than the oxidation of Malate to Oxaloacetate

How many ATP equivalents in total are produced per Acetyl CoA during Citric Acid Cycle including the oxidative phosphorylation and mitochondrial ATP synthase reactions?

a. 10 ATP

b. 9 ATP

c. 8 ATP

d. No ATP at all, only one GTP

Please answer both, I'll leave a good review :-)

Expert Solution

The questions given below are related to the citric acid cycle or the Krebs cycle or TCA cycle (tricarboxylic acid cycle).

It involves a series of chemical reactions.
It is used by all aerobic organisms to release stored energy.
Energy is released through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins, into ATP and CO2.

The oxidation of Succinate to Fumarate produces:

d. less ATP than the oxidation of Malate to Oxaloacetate

Description:

Oxidation of succinate to fumarate occurs during Krebs cycle.

The reaction is catalyzed by- Succinate Dehydrogenase.
Here one molecule of FAD is reduced to FADH2
This reduced FADH2 is subsequently oxidized by mitochondrial electron transport and produce ATP
Hence 1 molecule of FADH2 is oxidized to produce 2 ATP.

Oxidation of Malate to oxaloacetate is the final step in Krebs cycle.

It is catalyzed by malate dehydrogenase
Here one molecule of NAD+ is reduced to NADH + H+
One molecule of NADH2 is oxidised to give 3 ATP

How many ATP equivalents in total are produced per Acetyl CoA during Citric Acid Cycle including the oxidative phosphorylation and mitochondrial ATP synthase reactions?

b. 10 ATP

Description:

The products produced in a single citric acid cycle with one acteyl co enzyme A is
3 NADH2 , 1FADH2 and 1ATP
1NADH2 is 2.5 ATP Hence, 3 NADH2 = 7.5ATP
1FADH2 is 2 ATP
Therefore total ATP = 7.5 + 2+ 1=10.5 = approx 10 ATP

gladiator answered 2 years ago

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