Question

In: Chemistry

What are major disadvantages/issues of use of enzyme, instead of artificial catalysts? Describe 3 major issues...

What are major disadvantages/issues of use of enzyme, instead of artificial catalysts? Describe 3 major issues involving a use of enzyme in organic synthesis in general.

Solutions

Expert Solution

1. Cost - some enzymes are very very expensive. ATP is most often involved as phophorylating agent, other nucleoside triphosphates (NTP), including GTP, CTP, and UTP transfer the nucleoside phosphate moiety. In vivo, complex biosynthetic processes regulate the concentration of cofactors for reaction. As it is necessary to maintain one molecule of cofactor per turnover, the concentrations of cofactors are controlled with high efficiency. In enzyme-catalyzed organic synthesis, the high cost of cofactors has inhibited their use as stoichiometric reagents.

2. Substrate specificity: Enzymes can exhibit extremely high substrate specificities, which can be a problem if the enzyme doesn't accept your substrate.

3. Enzyme stability: Enzymes usually operate in an aqueous environment; they therefore tend to be more unstable in the organic solvents which are often required to solubilise the reacting substrate. The stability of enzymes in organic solvents depends on the hydrophilicity of the enzyme - hydrophilic enzymes tend to be less stable in organic solvents. Because enzymes must maintain specific three-dimensional shapes to retain catalytic activity.

Thank You So Much! Please Rate this answer as you wish.


Related Solutions

Describe 3 advantages and 3 disadvantages of the use of the emerging technology in the accounting...
Describe 3 advantages and 3 disadvantages of the use of the emerging technology in the accounting profession. For the advantages, you should describe how/why these are advantages to the accounting profession and for the disadvantages, you should describe why they are disadvantages, how serious these disadvantages are and whether there are any ways to overcome these disadvantages
what are 3 major healthcare issues and why are each of these a issue in todays...
what are 3 major healthcare issues and why are each of these a issue in todays day ?
Describe how catalysts work and give an example of one. What is the Kd for a...
Describe how catalysts work and give an example of one. What is the Kd for a catalyst and how would you interpret a low Kd. How do non-specific DNA binding proteins work? How do specific DNA binding proteins work?
What are the advantages and disadvantages of using steel instead of concrete to construct a bridge?...
What are the advantages and disadvantages of using steel instead of concrete to construct a bridge? explain in full detail any constraint involved
What is the major advantage of an S corporation, what are the disadvantages?
What is the major advantage of an S corporation, what are the disadvantages?
Describe in detail two of the challenges faced by the use of Artificial Intelligence (AI) in...
Describe in detail two of the challenges faced by the use of Artificial Intelligence (AI) in human life. Your answers must use at least three reference materials such as books, articles or websites, and must be clearly stated in writing. The description must be based on scientific arguments and accurate facts. The answer should be in two pages.
What are the advantages and/or disadvantages of owning preferred stock instead of its common stock of...
What are the advantages and/or disadvantages of owning preferred stock instead of its common stock of another company. If a parent company already owns a controlling interest in a company's common stock, why would it invest in any preferred stock of the subsidiary?
what are the major issues of monetary policy in Ghana
what are the major issues of monetary policy in Ghana
what are the 3 major parenting styles and describe the characteristic for each one
what are the 3 major parenting styles and describe the characteristic for each one
In 2-3 paragraphs answer the following. (Political Science: International Relations) What are the major environmental issues...
In 2-3 paragraphs answer the following. (Political Science: International Relations) What are the major environmental issues facing the international system? How are these problems interrelated? How can states and the international community address these environmental problems? What are the barriers to international environmental cooperation?
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT