In: Anatomy and Physiology
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Why do we call cardiac muscle to be a syncytium of many individual muscle cells? What is the name of membranes that connect longitudinally adjacent muscle cells?
As you know the mechanism of organophosphates involves irreversible inhibitors of AChE. Organophosphates have been used in several murders (VX used to kill the half-brother of North Korean dictator Kim Jong Un; Sarin gas used to kill 12 people on the Tokyo subway by the Japanese cult Aum Shinrikyo in 1995).The death of a victim is associated with difficulty of breathing and irregular heart rate. Please discuss the physiological mechanisms of organophosphates action on the lungs and on the heart.
An overweight 75 year old male with a history of coronary artery disease and shortness of breath on exertion celebrates his granddaughter’s wedding. He goes for several fast dances with the bride, after which he collapses on the floor, turns blue, and dies within minutes. What is the reason for his death?