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In: Biology

Immunology: A patient is immunocompromised and lived in a sterile environment at all times until his...

Immunology:

A patient is immunocompromised and lived in a sterile environment at all times until his death at age 1. Analysis of his DNA reveals a mutation in c-kit. Explain how the mutation affects the development of immune cells at the molecular level. Be specific.

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Expert Solution

Scientists discovered how a gene mutation affects T cell function to promote immune diaorders and then tested a treatment based on the discovery. Immune response determined by our genes. Scientists say they have found evidence that suggests genetics play a role in immune response, affecting our ability to fight off disease. Strong immune response to viruses, not the environment around us as previously belived. The genes passed to us by our parents play a bigger role in the body's disease fighting ability than scientists previously thought.

The action of immune system cells may lead to the destruction of mutated cells which can be regarded as the immune surveillance of mutation progression. Neoplastic cells are distroyed by immune cells with less magnitude of the pre- neoplastic cells.

Genetics play a role in immune response, affecting our ability to fight off disease. The adaptive immune system is involved in prompting the body to produce, store and transport cells and molecules in order to trigger specific responses toward of pathogens.


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