Question

short answers questions ( few breif sentenses ) all please

1) how does co2 transport by red blood cells differ from o2 transport by red blood cells

2)describe the genetic conditions regarding RH factor .Which might result in erthroblastosis fetalis ?

3) what are the two trends in erthrocyte maturation ?

4) if the mother has type A blood and the father has Type B . how it is possible that their child has type O blood ?

5) monocytes diffrentiate into multiple cell types , name the two types and what is the function of each type ?

Answer 1

Answer1= oxygen transport from lungs to tissues occur mostly (98 percent ) by haemoglobin as oxy haemoglobin present in RBCs and only 2 percent through dissolved in plasma.

Whereas CO2 transport from tiisues to lungs occur via=

70 percent through bicarbonate formation in plasma (HCO3-)

23 PERCENT via haemboglobin amd co2 complex present in RBCs as carboxy haemoglobin

7 percent via plasma ( dissolved form)

Answer2=Erythroblastosis fetalis is a immunological condition in which IG antibodies of mother cross the placenta , enters into fetal circulation and attack the antigen present on fetal RBCs leading to their destruction and hemolysis . Therefore it is also called HEMOLYTIC DISEASE OF NEWBORN.

CAUSE= this conditions occur when mother is Rh negative and fetus/ baby father is Rh positive .

Therefore this extra antigen in fetus which is not present in mother is considered foreign by mothers body and antibodies are formed against it .

Answer3= Erytrocyte maturation=

** haematopoietic stem cell ( multipotent stem cell) becomes unipotent stem cell and finally differentiate into Proerythroblast

** this converts into basophilic or early normoblast

** then to polychromatophilic or intermediate normoblast

**orthochromatic or late normoblast

** finally to reticulocyte and then to mature RBCs which are released into circulation.

As they mature, nucleo cytoplasmic ration decreases , chromatin condenses and colour of cell changes from blue to pink

Nucleus is also lost

Answer4 yes, they can have child with O blood group if parents are HETEROGYZOUS in theor blood group.

Ia Io ( heterozygous A Blood group) Ib Io( heterozygous B blood group)

Have 25 percent chances that they have o blood grouo child.