Find all possible pathogen associated molecular patterns (PAMPs) and their respective sensors as a table, including...

Find all possible pathogen associated molecular patterns (PAMPs) and their respective sensors as a table, including cell surface endosomal cytosolic sensors of PAMPs. Include human and mouse in your table. (YOU SHOULD MENTION TLR, NLR, CLR, and RLR)!!!

Expert Solution

PRRs (structure)		Adapters (structure)	PAMPs/Activators	Species
TLR	TLR1–TLR2 (LRR–TIR)	MyD88 (TIR–DD), TIRAP (TIR)	Triacyl lipopeptides	Bacteria
	TLR2–TLR6 (LRR–TIR)	MyD88 TIRAP	Diacyl lipopeptides	Mycoplasma
			LTA	Bacteria
			Zymosan	Fungus
	TLR2 (LRR–TIR)	MyD88, TIRAP	PGN	Bacteria
			Lipoarabinomannan	Mycobacteria
			Porins	Bacteria (Neisseria)
			tGPI-mucin	Parasites (Trypanosoma)
			HA protein	Virus (Measles virus)
	TLR3 (LRR–TIR)	TRIF (TIR)	dsRNA	Virus
	TLR4 (LRR–TIR)	MyD88, TIRAP, TRIF, TRAM (TIR)	LPS	Bacteria
	TLR4 (LRR–TIR)	MyD88, TIRAP, TRIF, TRAM (TIR)	Envelope proteins	Virus (RSV, MMTV)
	TLR5 (LRR–TIR)	MyD88	Flagellin	Bacteria
	TLR7 (LRR–TIR)	MyD88	ssRNA	RNA virus
	hTLR8 (LRR–TIR)	MyD88	ssRNA	RNA virus
	TLR9 (LRR–TIR)	MyD88	CpG DNA	Bacteria
			DNA	DNA virus
			Malaria hemozoin	Parasites
	mTLR11 (LRR–TIR)	MyD88	Not determined	Bacteria (uropathogenic bacteria)
	mTLR11 (LRR–TIR)	MyD88	Profilin-like molecule	Parasites (Toxoplasma gondii)
	NALP1/NLRP1 (CARD–FIND–NBD–LRR-PYD)	ASC	Anthrax lethal toxin	Bacteria
	IPAF/NLRC4 (CARD–NBD–LRR)		Flagellin	Bacteria
	NAIP5 (BIRx3–NBD–LRR)		Flagellin	Bacteria









CLR	Dectin-1 (lectin–ITAM)		?-Glucan	Fungi
RLR	RIG-I (CARDx2–helicase)	IPS-1 (CARD)	RNA (5’-PPP ssRNA, short dsRNA)	Virus
	MDA5 (CARDx2–helicase)	IPS-1	RNA (poly IC, long dsRNA)	Virus
	LGP2 (helicase)		RNA	Virus
NLR	NOD1/NLRC1 (CARD–NBD–LRR)	RICK (CARD), CARD9 (CARD)	iE-DAP	Bacteria
	NOD2/NLRC2 (CARDx2–NBD–LRR)	RICK, CARD9	MDP	Bacteria
	NALP3/NLRP3 (PYD–NBD–LRR)	ASC (PYD–CARD) CARDINAL (PYD–FIND)	MDP	Bacteria
			RNA	Bacteria, Virus
			ATP	Bacteria? Host?

gladiator answered 1 year ago

Describe the stages of phagocytosis. Explain how toll-like receptors and pathogen associated molecular patterns are involved...

Describe the stages of phagocytosis. Explain how toll-like receptors and pathogen associated molecular patterns are involved in the process of phagocytosis. list any organelles involved in the process.

10. Identify the false statement regarding antigens. A. antigens are pattern associated molecular patterns such as...

10. Identify the false statement regarding antigens. A. antigens are pattern associated molecular patterns such as peptidoglycan and LPS B. The adaptive immune system directly interacts with epitopes on an antigen C. Can result in enhanced killing by NK cells and recognition by phagocytes D. Only proteins can be recognized as antigens E. A and B F. B and C 11. Which is the correct statement regarding the complement cascade? A. The complement cascade is considered adaptive immunity because it...

In the real projective plane, list all possible + / - (positive and negative) patterns for...

In the real projective plane, list all possible + / - (positive and negative) patterns for three coordinates. Then match these triples to regions of the Fundamental Triangle. Also, describe the location of the usual four Euclidean quadrants in the Fundamental Triangle.

all possible elementary events associated with an experiment form?

Find all possible homomorphisms between Z and Z5.

Find all possible signatures induced by a nilpotent mapping on R5.

Write a description of all Newton’s Law, including any equations associated. For each law, provide a...

Write a description of all Newton’s Law, including any equations associated. For each law, provide a real-life example.

Find all of the inversions inversion taking (3, −5) to (3,5). Give all of the possible...

Find all of the inversions inversion taking (3, −5) to (3,5). Give all of the possible centers and their corresponding radii.

Find a possible formula for the trigonometric function whose values are in the following table. x...

Find a possible formula for the trigonometric function whose values are in the following table. x 0 2 4 6 8 10 12 y 8 2 -4 2 8 2 -4 y =

1. Find a possible formula for the trigonometric function whose values are in the following table....

1. Find a possible formula for the trigonometric function whose values are in the following table. X 0 2 4 6 8 10 12 Y 5 1 -3 1 5 1 -3 y=? 2. A population of rabbits oscillates 15 above and below an average of 128 during the year, hitting the lowest value in January (t = 0). Find an equation for the population, P, in terms of the months since January, t. P(t) = What if the lowest...

Question