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In: Biology

Are there any known inhibitors of hexokinase (highlight at least one and describe how it works)?

Are there any known inhibitors of hexokinase (highlight at least one and describe how it works)?

Solutions

Expert Solution

Glycolysis is processed by which glucose is broken down into two pyruvates. The process occurs in the cytosol. It is a 10 step process, and 3 steps are reversible, their reversible steps are catalyzed by hexokinase, phosphofructokinase, and pyruvate kinase.

Glucose is converted into glucose 6 phosphate, by hexokinase. Hexokinase is inhibited by glucose 6 phosphate, its product.

The high concentration of glucose 6 phosphates, a signal cell that there is no need for glucose for energy.

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