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In clinical laboratory testing, how can we minimize pre-analytical, analytical and post-analytical errors? please i need...

In clinical laboratory testing, how can we minimize pre-analytical, analytical and post-analytical errors?
please i need a Complete, not brief answer (detailed)

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Answer:

  • The laboratory testing process is divided to three main phases.
  • They are Pre-analytical,Analytical and Post-analytical.
  • Preanalytical phase of laboratory testing includes ordering,collection,handling transportation and reception of the samples.
  • Analytical phase includes the testing of the specimen collected
  • Post-analytical phase includes interpretation of the results,generating a report,storage,follow up and retesting if needed
  • An error in laboratory is any defect occuring in any of these phases resulting the quality of results.
  • It affects the patient by causing a misdiagnosis and wrong treatment.
  • The errors may also lead to a fatal reaction.So minimizing errors during a lab test is very important.

In order to avoid pre-analytical errors these steps can be taken

  • Be aware of the current developments in testing
  • Technological advances such as barcoding,radiofrequency identification or wristbands can help the patient identification.
  • Standardizing the collection products helps reduce errors.
  • For example components of blood collection tubes like tube walls,anticoagulants,clot activators can affect the accuracy.So it should always be standardized.
  • when collecting specimen the individual should confirm the prerequisites like last food intake,time of a drug intake etc.Labelling should contain two patient identifiers.
  • inadequate specimen volume or contamination of the specimen should be avoided
  • Written protocols that explains all the standard procedures helps to reduce error.
  • Any new test equipment should be tested first.
  • Special attention should be given while transporting the specimen.Improper temperature,storage also can lead to errors and to be avoided.

In order to avoid analytical errors these steps can be followed:

  • The analytical quality can be improved by internal quality controls.
  • New automated technologies can reduce the analytical errors to a great extend.
  • Some type of antibodies may cause changes in measurements causing interference.So those informations should be checked before analyzing.
  • Equipments should be checked for any malfunction.
  • Procedures for analyzing th especimen should be strictly followerd to reduce errors.
  • External Quality Assessment helps monitor the quality status of internal procedures.

Post-analytical errors can be minimized by

  • Proper validation of the reports should be done
  • Processing the results to a report form should be assessed.
  • Avoiding mininterpretation of the results.
  • Critical results must be reported promptly.
  • Transcription errors should be avoided.
  • Turn around time is important.The results should be delivered on time.

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