ASTHMA
Definition:
Asthma is a chronic inflammatory
disorder of the airways. This inflammation causes an increase in
airway hyperresponsiveness that leads to recurrent episodes of
wheezing, breathlessness, chest tightness, and cough, particularly
at night or in the early morning.
Triggers of Asthma Attacks
Etiology is idiopathic.
- Allergens; Allergic asthma maybe
seasonal and related to allergies such as tree or weed pollen.
- Exercise; Asthma that is induced or
exacerbated during physical exertion is called exercise induced
asthma.
- Air pollutants; Exhaust fumes,
perfume, Oxidants, sulfer dioxide, cigarette smoke, aerosol
sprey
- Viral upper respiratory
infections
- Sinusitis
- Stress
- Drugs; Aspirin, Nonsteroid
antiinflammatory drugs, beta Adrenergic blockers.
- Occupational exposure; metal salts,
wood and vegetable dusts, industrial chemical and plastic,
pharmaceutical agents.
- Food additives; sulfites,
monosodium glutamate, tartrazine.
- Hormones/ menses
11. Gastroesophageal reflux
disease.
Diagnostic
studies
Diagnostic
- history and physical examination
- Pulmonary function studies including response to bronchodilator
therapy
- Peak expiratory flow rate.
- Chest X-ray
- Measurements of ABGs or oximetry
- Allergy skin testing (if indicated)
- Blood level of eosinophils and IgE (if indicated)
- Nitric oxide levels
Collaborative
Therapy
- Mild intermittent or persistent
Asthma
- Identification and
avoidance/elimination of triggers.
- Desensitization (immunotherapy) if
indicated
- Patient and family teaching to drug
therapy
- Drug therapy
- Asthma action plan
- Status Asthmaticus
- SaO2 monitoring
- ABGs
- Inhaled beta2 Adrenergic
agonists or anticholinergic agents
- O2 by mask or nasal
prongs
- IV or oral corticosteroid
- IV fluids
- IV magnesium
- Intubation and assisted
ventilation
Drug therapy
Long term control medications
- Antiinflammatory drugs
- Corticosteroids
- Cromolyn and nedocromal
- Leukotriene modifiers
- Omalizumab
- Bronchodilator
- Long acting inhaled
beta2 Adrenergic agonists
- Long acting oral beta2
Adrenergic agonists
- Theophylline
Quick Relief Medications
- Bronchodilator
- Short acting inhaled
beta2 Adrenergic agonists
- Anticholinergic
- Antiinflammatory drugs
- Corticosteroids.