In: Biology
Explain how the immune system responds to a pathogen before and after vaccination?
When the immune system is alerted that something foreign has entered the body. Triggers include the release of chemicals by damaged cells and inflammation and changes in blood supply to an area of damage which attract white blood cells.
White blood cells destroy the infection, convey chemical messages to other parts of the immune system. As blood and tissue fluids circulate around the body, various components of the immune system are continually surveying for potential sources of attack or abnormal cells.
Immune system response initially involves the production of antibodies that can bind to a particular antigen and the activation of antigen-specific white blood cells.
Vaccination can increase the levels of circulating antibodies against a certain antigen. Antibodies are produced by a type of white blood cell called B cells. Each B cell can only produce antibodies against one specific epitope. When activated, B cell will multiply to produce more clones able secrete that particular antibody.