Question
In: Biology
The histone proteins of nucelosomes are often abnormally modified in cancer cells, leading to _____. a....
The histone proteins of nucelosomes are often abnormally modified in cancer cells, leading to _____.
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a. an alteration in chromatin structure |
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b. an alteration in levels of transcription |
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c. double-stranded breaks in DNA |
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d. All of the above |
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e. Both a and b |
Solutions
gladiator answered 1 year agoRelated Solutions
Ras is a GTP-binding protein that is often mutated in cancer cells. Normal cells are stimulated...
Ras is a GTP-binding protein that is often mutated in cancer
cells. Normal cells are stimulated to divide by receiving a signal
from a growth factor through a receptor tyrosine kinase. When the
receptor tyrosine kinase binds the growth factor, Ras is stimulated
to bind GTP. Ras in turn activates proteins that promote cell
proliferation. A common mutation in cancerous cells causes Ras to
behave as though it were bound to GTP all the time. Suppose that
there is a...
n cancer cells, chromatin around proto-oncogenes and tumor suppressors is often changed in comparison to cells...
n cancer cells, chromatin around proto-oncogenes and tumor
suppressors is often changed in comparison to cells that are not
cancerous. Considering that higher expression of proto-oncogenes
and lower expression of tumor suppressors (in comparison to normal
cells) could lead to a cancerous phenotype, would you expect that
the following changes/differences in chromatin in cells could lead
to a cancerous phenotype?
"Higher levels of HATs around proto-oncogenes"
What types of proteins are writers of the histone code and what is their general function?
What types of proteins are writers of the histone code and what
is their general function?
Cell Cancer: a. In what ways are cancer cells different from normal cells in terms of...
Cell Cancer:
a. In what ways are cancer cells different from normal
cells in terms of properties and behavior?
b. What is the difference between an oncogene and a
tumor suppressor gene?
Neutropenia is an abnormally low number of neutrophils in the blood. Chemotherapy often reduces the number...
Neutropenia is an abnormally low number of neutrophils in the
blood. Chemotherapy often reduces the number of neutrphils to a
level that makes patients susceptible to fever and infections. G.
Bucaneve et al. published a study of such cancer patients in the
paper "Levofloxacin to Prevent Bacterial Infection in Patients With
Cancer and Neutropenia" (New England Journal of Medicine, Vol. 353,
No. 10, pp. 977-987). For the study, 375 patients were randomly
assigned to receive a daily dose of levofloxacin,...
Neutropenia is an abnormally low number of neutrophils in the blood. Chemotherapy often reduces the number...
Neutropenia is an abnormally low number of neutrophils in the
blood. Chemotherapy often reduces the number of neutrphils to a
level that makes patients susceptible to fever and infections. G.
Bucaneve et al. published a study of such cancer patients in the
paper "Levofloxacin to Prevent Bacterial Infection in Patients With
Cancer and Neutropenia" (New England Journal of Medicine, Vol. 353,
No. 10, pp. 977-987). For the study, 375 patients were randomly
assigned to receive a daily dose of levofloxacin,...
What activities of a eukaryotic cell would be affected by dysfunctional histone proteins that can’t properly...
What activities of a eukaryotic cell would be affected by
dysfunctional histone proteins that can’t properly condense the DNA
into nucleosomes?
How would these activities be affected?
Chemical modifications of histone tails are often made in chromatin to change the amount of chromatin...
Chemical modifications of histone tails are often made in
chromatin to change the amount of chromatin compaction. Name three
chemical modifications that have been observed by scientists to be
on histone tails in chromatin. the modifications that you listed
and discuss whether that modification is associated with closed or
open chromatin.
Highly invasive cancer cells usually express less __________, a key adhesion molecule. Cancer cells secrete an...
Highly invasive cancer cells usually express less __________, a
key adhesion molecule.
Cancer cells secrete an activator of the enzyme ________ to
degrade basal lamina and extracellular matrix and activate matrix
metalloproteinases.
An individual can inherit a gene in which expression has been
altered by an __________ change with no mutation of the gene
sequence.
Finding the _____ ________ virus in chickens established the
first association between viral infection and cancer.
Which histone modifications are bound by Bromodomain containing proteins? Which modifications are bound by Chromodomains? Which...
Which histone modifications are bound by Bromodomain containing
proteins? Which modifications are bound by Chromodomains? Which are
associated with “opening” and which with “closing” of
chromatin?
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