Question

1. Highly invasive cancer cells usually express less __________, a key adhesion molecule.
2. Cancer cells secrete an activator of the enzyme ________ to degrade basal lamina and extracellular matrix and activate matrix metalloproteinases.
3. An individual can inherit a gene in which expression has been altered by an __________ change with no mutation of the gene sequence.
4. Finding the _____ ________ virus in chickens established the first association between viral infection and cancer.

Answer 1

1. Highly invasive cancer cells usually express less __________, a key adhesion molecule.

The answer to this will be E cadherin. These are the main key adhesion molecules. They help in the attachment of one cell with another.

1. Cancer cells secrete an activator of the enzyme ________ to degrade basal lamina and extracellular matrix and activate matrix metalloproteinases.

The enzyme produced will be plasmin. As it degrades basal lamina and extracellular matrix.

1. An individual can inherit a gene in which expression has been altered by an __________ change with no mutation of the gene sequence.

These changes are called epigenetic changes. These changes are not due to a mutation in the DNA. These changes occur due to covalent modification of DNA and histones.

1. Finding the _____ ________ virus in chickens established the first association between viral infection and cancer.

The virus which was discussed in chicken was Rous Sarcoma Virus.