How many rounds of β-oxidation are necessary for the complete oxidation of stearic acid (18:0)? How...

How many rounds of β-oxidation are necessary for the complete oxidation of stearic acid (18:0)? How many molecules of NADH, FADH2,and Acetyl CoA are generated? Assuming that the Acetyl CoA is further metabolized by the citric acid cycle, how many more NADH, FADH2and GTP are generated? Starting with free stearate in the cytosol, how many ATP are generated by the complete oxidation of stearate to CO2followed by oxidative phosphorylation of the produced NADH and FADH2?

Expert Solution

Ans.

How many rounds of β-oxidation are necessary for the complete oxidation of stearic acid (18:0)?

8 rounds of β-oxidation are necessary for the complete oxidation of stearic acid (18:0).

How many molecules of NADH, FADH2, and Acetyl CoA are generated?

35 molecules of NADH, 17 molecules of FADH2, and 9 molecules of Acetyl CoA are generated.

NADH =(8+27)=35 [ 8 for 8 rounds and 27 from 9 Krebs cycle of 9 acetyl CoA (9×3 =27)
FADH2 =(8+9)=17 [ 8 for 8 rounds and 9 from 9 Krebs cycle of 9 acetyl CoA (9×1=9]
Acetyl CoA =9

Assuming that the Acetyl CoA is further metabolized by the citric acid cycle, how many more NADH, FADH2and GTP are generated?

NADH =(9×3)=27
FADH2 =(9×1)=9
GTP =(9×1)=9

Starting with free stearate in the cytosol, how many ATP are generated by the complete oxidation of stearate to CO2 followed by oxidative phosphorylation of the produced NADH and FADH2?

ATP = (ATP from NADH)+(ATP from FADH2)+(ATP which is similar to GTP)
= (24+81)+(16+18)+(9)
= 148

gladiator answered 2 years ago

1) Consider the oxidation of Stearic acid (18 carbon fatty acid, fully saturated) to CO2, NADH...

1) Consider the oxidation of Stearic acid (18 carbon fatty acid, fully saturated) to CO2, NADH and FADH2 a) How many moles of electrons are removed from a molecule of stearic acid during the oxidation process? b) How many moles of electrons are removed during the oxidation of a mole of glucose? c) How many moles of electrons are removed during the oxidation of 100 g of stearic acid? d) How many moles of electrons are removed during the oxidation...

For the structure of Myristic acid: How mạny rounds of β-oxidạtion will tạke plạce upon complete...

For the structure of Myristic acid: How mạny rounds of β-oxidạtion will tạke plạce upon complete oxidạtion of this fạtty ạcid? How mạny FẠDH2 ạnd NẠDH will be formed from the β -oxidạtion (only)? How mạny ạcetyl-CoẠ molecules will be formed from the β -oxidạtion? How mạny totạl ẠTP will be mạde from complete oxidạtion of myristic ạcid?

Describe the β-oxidation of the fatty acid palmitate. biochemistry

SHOW ALL WORK PLEASE! Compare the amounts of ATP (per carbon) generated from β-oxidation of stearic...

SHOW ALL WORK PLEASE! Compare the amounts of ATP (per carbon) generated from β-oxidation of stearic acid (18:0) to the amount of ATP generated from glucose during cellular respiration.

18. How many ATP can be produced by the complete oxidation of each propionyl-CoA product of...

18. How many ATP can be produced by the complete oxidation of each propionyl-CoA product of fatty acid oxidation? Compare this to the ATP yield for each acetyl-CoA.

Calculate the number of ATP molecules produced by complete β−oxidation of the fourteen-carbon saturated fatty acid...

Calculate the number of ATP molecules produced by complete β−oxidation of the fourteen-carbon saturated fatty acid tetradecanoic acid (common name: myristic acid). THE ANSWER IS NOT 92!!!

Describe the β-oxidation of the fatty acid palmitate. biochem question

1. Which of the following is NOT a product of β-oxidation of a 20-carbon fatty acid?...

1. Which of the following is NOT a product of β-oxidation of a 20-carbon fatty acid? A. 10 acetyl-CoA B. 10 NADH C. 9 FADH2 2. Which pathway is NOT active in the liver in the well-fed state? A. glycolysis B. fatty acid synthesis C. glycogenesis D. gluconeogenesis 3. Beriberi is a condition caused by a thiamine deficiency. When analyzing blood samples of an individual with Beriberi, what would you expect to find elevated levels of? A. pyruvate B. glutamate...

Topic : Fatty Acid Catabolism 4.How many rounds of the TCA cycle will be used to process...

Topic : Fatty Acid Catabolism 4.How many rounds of the TCA cycle will be used to process the acetyl-CoA produced from β-oxidation of palmitic acid? How many NADH and how many FADH2 will this produce? How many ATP will be made by substrate-level phosphorylation? 5. Given the entry points of NADH and FADH2 produced by β-oxidation into the ETS, how many net ATP can be obtained from the complete oxidation of palmitic acid? (Don’t forget that some ATP was consumed in...

For each of the following acid-base reactions, calculate how many grams of each acid are necessary...

For each of the following acid-base reactions, calculate how many grams of each acid are necessary to completely react with and neutralize 2.8 g of the base. Part A : HCl(aq)+NaOH(aq)→H2O(l)+NaCl(aq) Part B : 2HNO3(aq)+Ca(OH)2(aq)→2H2O(l)+Ca(NO3)2(aq) Part C : H2SO4(aq)+2KOH(aq)→2H2O(l)+K2SO4(aq) Express your answer using two significant figures.

Question