Question

T or F For the following

Acetylenic fatty acids are natural products.

Platelet-activating factor (PAF) is a natural product

Eicosapentaenoic acid (EPA) 20:5 (5c,8c,11c,14c,17c) cannot be formed from acetyl-CoA and malonyl-CoA by animal biosynthetic processes alone

Eicosapentaenoic acid (EPA) 20:5 (5c,8c,11c,14c,17c) It is formed by the acetate pathway

Prostaglandins They are primary metabolites

Prostaglandins They are formed by the acetate pathway

Answer 1

Acetylenic fatty acids are natural products.

False.

Acetylenic fatty acids contain triple bonds. Generally, these are prepared synthetically in labs. Only some are found in natural oils.

Platelet-activating factor (PAF) is a natural product.

True.

PAF is produced by platelets, endothelial cells, neutrophils, macrophages, etc, as an immune response.

Eicosapentaenoic acid (EPA) 20:5 (5c,8c,11c,14c,17c) cannot be formed from acetyl-CoA and malonyl-CoA by animal biosynthetic processes alone

False.

EPA cannot be synthesized by animals from acetyl-CoA and malonyl-CoA alone. Animals lack enzymes to introduce double bonds beyond carbon 9 and 10. Therefore, linoleic acids (LA) and linolenic acids (ALA), the precursors for longer chain fatty acids, must be collected from the diet. After that, animals can synthesize EPA from LA and ALA.

Eicosapentaenoic acid (EPA) 20:5 (5c,8c,11c,14c,17c) It is formed by the acetate pathway

False.

EPA cannot be formed by acetate pathway.

Prostaglandins They are primary metabolites

True.

They are formed from arachidonic acid and involved in the regulation of blood pressure, reproduction, and normal growth.

Prostaglandins They are formed by the acetate pathway

False.

They are formed by cyclooxygenase pathway.