If a student accidentally ran their TLC plate with 30%
hexane/ether (instead of the 30% ether/hexane...
If a student accidentally ran their TLC plate with 30%
hexane/ether (instead of the 30% ether/hexane as directed), briefly
explain who their TLC results would differ.
If a TLC plate was done in acetone and hexane which would have a
higher rf value:
1. Benzenaldehyde or 1,4-Pentadien-3-one, 1,5-diphenyl-?
2.Benzenaldehyde or
2,2’-(phenylmethylene)bis(5,5-dimethylcyclohexane-1,3-dione)?
3. Benzenaldehyde or
3,3,6,6-tetramethyl-9-phenyl-3,4,5,6,7,9-hexahydro-1H-xanthene-1,8(2H)-dione?
(3) A student accidentally uses toluene to
triturate their crude product instead of methanol. Moments after
heating, their crude product dissolves completely.
Explain why the result was undesirable, drawing comparisons
between recrystallization and trituration.
Propose a solution to recover the student’s product involving a
technique utilized in this lab.
Explain the difficulty using the technique proposed in (b) with
the solvent that the student has dissolved their product in.
d. Propose a solution to the problem above.
A TLC plate showed two spots with Rf values of 0.25 and 0.26. The plate was removed from the developing chamber, the residual solvent was allowed to evaporate from the plate, and then the plate was returned to the developing chamber. What would you expect to see after the second development was complete?
A TLC plate showed two spots of Rf 0.25 and 0.26. The plate was
dried carefully, and returned to the developing chamber. What would
you expect to see after the second development was complete?
ORGANIC CHEMISTRY (TLC lab)
if you used a solution of 90% ethyl acetate / 10% hexane instead
of 10% ethyl acetate / 90% hexane to elute your TLC plates, what
would you expect to see?
Would the Rf valaues increase of decrease for each compound?
Explain in detail.
Rf values
Naphthalene = 0.44
9-fluorene 0.56
Benzophenone = 0.39
Fluorene = 0.88
4-nitroaniline = 0.28
4- methoxyacetophenone = 0.24
A developed TLC plate was examined under UV light. Was it a
necessary step if both ferrocene and acetylferrocene are visible
without a visualization method? Why or why not?
I need at least a paragraph response to this
question!
if youre doing an analysis with a tlc plate and you use ethyl
actete (polar) as the solvent please rank the distance that these
molecules would move (aka which one would be the highest on the
plate). They are the same molecule, the only thing that changes is
the functional group. One has an alcohol functional group, one has
a ketone, and the other has alkene functional group
Mivacurium (Mivacron), instead of metronidazole, was
accidentally administered to several patients at a large hospital.
Three patients went into respiratory arrest, and one died. A
multidisciplinary team was assembled to analyze the event and
determine actions that could be taken to prevent similar errors
from recurring. Here’s what they found: A technician pulled several
bags of foil-wrapped IV items from the bulk IV storage area. At the
time, it was thought that metronidazole was the only medication in
the pharmacy...