In: Anatomy and Physiology
Create a table of the different classes of neurotransmitters. List names of neurotransmitters, their implications in human disease, and their main functions .
There are hundreds of neurotransmitters, but they can be grouped into classes depending on their structure, or function.
Based on their function and action they can be classified as excitatory, inhibitory or neuromodulators.
Type | Names | function | disease |
Exicatory | Glutamate | role in learning and memory, particularly in the process of long-term potentiation. | Excess glutamate can cause Parkinson's disease, multiple sclerosis, Alzheimer's disease,etc |
Inhibitory | GABBA | regulating neuronal activity; anxiety and sleep. | Decreased GABA activity can cause Attention Deficit Hyperactivity Disorder (ADHD) |
Neuromodulators | Endorphins | Involved in pain regulation | Decreased levels can cause condition like mental illness such as obsessive-compulsive disorder. |
Based on structures they can be classifed as,
Type | Name | function | disease |
Monoamines | Adrtenaline,noradrenaline, | They are the flight/fight hormones that are released when the body is under extreme stress | Excess adrenaline can cause heart damage, insomnia, a jittery, nervous feeling. |
Amino acid | Glycine | As an inhibitory neurotransmitter glycine is important in many motor and sensory functions, | high doses of glycine could make the damage caused by a stroke worse |
Peptides | Oxytocin | helps in dialtion of uterus to assist child birth. | A lack of oxytocin in a nursing mother would prevent the milk-ejection reflex and prevent breastfeeding. |
Others | Acetylcholine | is an excitatory neurotransmitter which is involved in stimulation of muscle fibers | Excess acetylcholine can cause uncontroled muscle contraction. |