In: Anatomy and Physiology
The rate of being diagnosed with colorectal cancer is higher among AfricanAmericans than among any other population group. Genetic or biological factors and socioeconomic factors play a big role in high incidence of colon cancer among these population group. Approximately 30-50% of colorectal tumors are known to have a mutated KRAS gene, KRAS mutations in colon cancers have been associated with a poorer survival and increased tumor aggressiveness, the frequency of KRAS gene mutation is more among these population group, African Americans with colorectal cancer are more likely to cope with an aggressive subtype fueled by a mutation in the KRAS gene, which drives cancer growth. This cancer in black people also occurs more often on the right side of the colon, another factor that can lead to poor prognoses or diagnosis. Diet, tobacco use and a lack of access to equal medical treatment options may increase the risk of developing colorectal cancer.among these population.There is evidence that African-Americans are less likely than whites to have screening tests for colorectal cancer hence increasing the risk of colorectal cancer.