In: Anatomy and Physiology
a. what is the probability that Joe will also develop the disease?
b. Joe and his new wife have been eager to start a family. What is the probability that their first child will eventually develop the disease?
case 1
widow peak is recessive allele
mother prebred with no widow peak WW
father with widow peak ww
father allele left to right mother allele down |
w | w |
W | Ww | Ww |
W | Ww | Ww |
phenotypic ratio ; ALL non widow peak
genotypic ratio all hybrid
case 2 mother is Bb hetrogygous brown
father is bb homozygous white
father left to right mother down |
b | b |
B | Bb | Bb |
b | bb | bb |
phenotypic ratio : 2 brown : 2 white
genotypic ratio - 2 hybrid : 2 pure recessive breed
case 3 albinism recessive allele
Two normal parents have an albino child. What are the parents’ genotypes? What is the probability that the next child will be albino
parents must be hybrid
Aa Aa
child is aa
father left to right mother down |
A | a |
A | AA | Aa |
a | Aa | aa |
phenotyic ratio of children for these parents 3 normal :1 albinic
genotypic ratio = 1:2:1
next child to be albino probability - 25%
case 4 joe father have huntington disease Hh
mother is hh no disease
a huntington disease is autosomal dominant disease
father left to right mother down |
H | h |
h | Hh | hh |
h | Hh | hh |
probabiilty of joe to be suffered is 50%
b if joe is suffered from huntigton disease then probability in children is 50%