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Molecular Cell Biology List the two changes affecting chromosomes that make chromosome segregation during meiosis one...

Molecular Cell Biology

List the two changes affecting chromosomes that make chromosome segregation during meiosis one different from chromosome segregation during mitosis (do not mention microtubules in your answer).

Solutions

Expert Solution

  • chromosome segregation is a process occur in eukaryotes, in which the two sister chromatids separate each other and migrate to opposite poles of nucleus.
  • In first, the segregation of chromosomes occur in two phases of meiosis known as anaphase1 and anaphase 2   During the “interphase s” each of the chromosomes in the diploid cell is converted into two copies of same chromosomes called chromatids. These chromatids then pair with the homologous chromosome present in the same nucleus. This process is called synapsis. During synapsis, genetic recombination also occurs. After recombination, chromosome segregation occurs.
  • in second , segregation during meiosis occurs in prophase 2. In this phase there is no round of DNA replication and hence the two chromatids comprising each chromosome split into different nuclei, so that each nucleus consist of single set of chromatids . This segregation is mediated by cohesin. The improper segregation during prophase 2 can lead to aneuploid gametes.

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