In: Anatomy and Physiology
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In 800 APA essay discuss the control of thyroid gland and hyper and hyposecretion from it on the body
or close to 800 words
The thyroid gland is an endocrine gland in a neck. It makes two hormone that are secreted by into the blood i.e.
1) Thyroxine {T3}
2) Triiodothyronine {T4}
Both. T3 and T4 have a similar effect on target cells. I most target tissue T4 is convert to T3.
They influence the metabolic rate, development and growth.
T3 production is regulated by negative feedback mechanisms.
Hypothalamus control the secretion if thyroid.
The thyroid cells that synthesized T4 and T3 take up circulating iodine from the blood and attached them to tyrosine residues in the protein thyroglobulin.
Molecules of throsine combine with thryoxine , which combine with thyroglobulin.
This action are stimulate by the bonding of TSH.
The chief stimulator of thyroid hormone synthesis is thyroid stimulating hormone from the anterior pituitary binding of TSH to receptors on thyroid epithelial seems to enhance all of the
Processes necessary for synthesis of thyroid hormone.
Including synthesis of the iodide transporte,thyroid peroxidase and thyroglobulin.
The thyroid gland is part of hypothalamic pituitary thyroid axis.
It control of thyroid hormone secretion is excrete negative feedback.
Brain center---> TRH----> TSH-----> thyroid hormone
Hyposecreation of thyroid hormone cause hypothyroidism.
It result in lethargy and weight gain
In child ,dwarfism mental retardation seens.
Also, increase secreation of hormone known as a hyperthyroidism ,which causes increased heart rate. Increase blood pressure, weight loss
Iodine also plays key role in thyroid control.
Thyroid also produced calcitonin.