Question

What cytoskeleton filaments and molecular motors are involved in HIV trafficking?

Answer 1

Answer. Cytoskeleton filaments are involved in HIV trafficking :Throughout transmission, HIV uses the host cytoskeleton to travel across the cytoplasm to the nucleus where it incorporates its genome.

Results: Microtubule-associated proteins (MAP1A and MAP1S) facilitate the movement of HIV to the nucleus. Conclusion: MAP1 proteins help to spread viral capsids to microtubules.

And other points including : Generally HIV-1 binds non-polarized cells to the plasma membrane independently of the cytoskeleton. Remember that the transport of Env through the clandestine route is not shown.

Assembly in chronically infected macrophages occurs in invaginated regions of the plasma membrane enriched by tetraspanins, which are stabilized by actin cytoskeleton.

Molecular motor are involved in HIV trafficking: Molecular motors are a class of proteins that drive intracellular trafficking by translating chemical energy into mechanical work along cytoskeletal filaments. While kinesins and dynes drive microtubule-based transport, myosins drive actin-based transport.

Recent HIV studies have identified different molecular motors involved in the trafficking of these viral particles. Viral elimination of cytoskeletal transport systems The cytoplasm of eukaryotic cells is a complex and molecularly crowded environment in which proteins travel mainly through diffusion.