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Give a brief review on the evolution in computer generations. A common application of the fifth...

Give a brief review on the evolution in computer generations. A common application of the fifth generation is the Expert system. Describe how it can be applied in the medical field.

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First Generation: Vacuum Tubes (1940-1956)

The first computer systems used vacuum tubes for circuitry and magnetic drums for memory, and were often enormous, taking up entire rooms. These computers were very expensive to operate and in addition to using a great deal of electricity, the first computers generated a lot of heat, which was often the cause of malfunctions. First generation computers relied on machine language, the lowest-level programming language understood by computers, to perform operations, and they could only solve one problem at a time. It would take operators days or even weeks to set-up a new problem. Input was based on punched cards and paper tape, and output was displayed on printouts.

Second Generation: Transistors (1956-1963)

The world would see transistors replace vacuum tubes in the second generation of computers. The transistor was invented at Bell Labs in 1947 but did not see widespread use in computers until the late 1950s. The transistor was far superior to the vacuum tube, allowing computers to become smaller, faster, cheaper, more energy-efficient and more reliable than their first-generation predecessors. Though the transistor still generated a great deal of heat that subjected the computer to damage, it was a vast improvement over the vacuum tube. Second-generation computers still relied on punched cards for input and printouts for output.

Third Generation: Integrated Circuits (1964-1971)

The development of the integrated circuit was the hallmark of the third generation of computers. Transistors were miniaturized and placed on silicon chips, called semiconductors, which drastically increased the speed and efficiency of computers. Instead of punched cards and printouts, users interacted with third generation computers through keyboards and monitors and interfaced with an operating system, which allowed the device to run many different applications at one time with a central program that monitored the memory. Computers for the first time became accessible to a mass audience because they were smaller and cheaper than their predecessors.

Fourth Generation: Microprocessors (1971-Present)

The microprocessor brought the fourth generation of computers, as thousands of integrated circuits were built onto a single silicon chip. What in the first generation filled an entire room could now fit in the palm of the hand. The Intel 4004 chip, developed in 1971, located all the components of the computer—from the central processing unit and memory to input/output controls—on a single chip. In 1981 IBM introduced its first computer for the home user, and in 1984 Apple introduced the Macintosh. Microprocessors also moved out of the realm of desktop computers and into many areas of life as more and more everyday products began to use microprocessors.

Fifth Generation: Artificial Intelligence (Present and Beyond)

Fifth generation computing devices, based on artificial intelligence, are still in development, though there are some applications, such as voice recognition, that are being used today. The use of parallel processing and superconductors is helping to make artificial intelligence a reality.

Quantum computation and molecular and nanotechnology will radically change the face of computers in years to come. The goal of fifth-generation computing is to develop devices that respond to natural language input and are capable of learning and self-organization.

Common Application of 5th Generation is:

Artificial Intelligence, Parallel Processing, Voice Recognition, Quantum Computation

Expert System in Artificial Intelligence:

An Expert System is defined as an interactive and reliable computer-based decision-making system which uses both facts and heuristics to solve complex decision-making problems. It is considered at the highest level of human intelligence and expertise. It is a computer application which solves the most complex issues in a specific domain.

The expert system can resolve many issues which generally would require a human expert. It is based on knowledge acquired from an expert. It is also capable of expressing and reasoning about some domain of knowledge. Expert systems were the predecessor of the current day artificial intelligence, deep learning and machine learning systems.

Expert systems, or decision support systems, are artificial intelligence systems that have been trained with real cases to perform complicated tasks. They are used in a variety of areas and are among the most popular application fields in artificial intelligence. Expert systems have applications in different areas of medicine. Here we present a short history of medical expert systems and the characteristics of these systems. Medical expert systems were initially developed for academic areas and later for clinical applications also. Health care systems produce tremendous amounts of information (patient, demographic, clinical and billing data), which are susceptible to analysis by intelligent software and need new techniques to extract new knowledge. A variety of medical expert systems tools are available and can function as intelligent assistants to clinicians, helping in diagnostic processes, laboratory analysis, treatment protocol, and teaching of medical students and residents.

Examples of Expert Systems

Following are examples of Expert Systems

  • MYCIN: It was based on backward chaining and could identify various bacteria that could cause acute infections. It could also recommend drugs based on the patient's weight.
  • DENDRAL: Expert system used for chemical analysis to predict molecular structure.
  • PXDES: Expert system used to predict the degree and type of lung cancer
  • CaDet: Expert system that could identify cancer at early stages

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