Question

Which of the following statements describes the Haldane effect?

Select one:

a. Increasing the partial pressure of oxygen decreases the ability of carbon dioxide to bind hemoglobin

b. Decreasing the partial pressure of oxygen increases the ability of carbon dioxide to bind hemoglobin

c. Increasing the partial pressure of oxygen increases the ability of carbon dioxide to bind hemoglobin

d. Both a and b

e. Both b and c

Answer 1

Which of the following statements describe the Haldane Effect:-d). Both a and b.

a).Increasing the partial pressure of oxygen decreasing the ability of carbondioxide to bind hemoglobin.

b).Decreasing the partial pressure of oxygen increases the ability of carbondioxide to bind hemoglobin.

Haldane effect is the effect by which combination of oxygen with hemoglobin displaces carbon dioxide from hemoglobin. Excess of oxygen content in blood causes shift of the carbon dioxide dissociation curve to right.

*Causes for Haldane effect= Due to the combination with oxygen, hemoglobin becomes strongly acidic. It causes displacement of carbon dioxide from hemoglobin in two ways:-

1). Highly acidic hemoglobin has low tendency to combine with carbon dioxide. So, carbon dioxide is displaced from blood.

2). Because of the acidity, hydrogen ions are released in excess. Hydrogen ions bind with bicarbonate ions to form carbonic acid. Carbonic acid in turn dissociates into water and carbon dioxide. Carbon dioxide is released from blood into alveoli.

*Significance of Haldane effect = Haldane effect is essential for: 1. Release of carbon dioxide from blood into the alveoli of lungs 2. Uptake of oxygen by the blood.