You have identified a Type 1 transposable element in yeast. This transposon has a small mutation...

You have identified a Type 1 transposable element in yeast. This transposon has a small

mutation that inactivates its only protein-encoding gene. If you provide this transposon

with an external source of transposase, would you expect this transposon to be able to

move?

Why or why not?

Expert Solution

Ans: Type 1 transposable elements are also known as retrotransposons and acts by copy and paste mechanism. This means that the original transposons remain in place while a copy inserted at the new position. In retrotransposons first the DNA is transcribed into RNA and this RNA copies itself and the new copy reverse transcribed into cDNA and inserted in the genome using the enzyme transposase.

We can also classify transposons into Autonomous (they have everything they need to promote their own transposition) and Non Autonomous ( they dont have functional transposase enzyme and require transposase from the others for transposition). So in the question it is given that the mutation inactivates its only protein coding gene so this retrotansposon converts to Non autonomous type. We are providing transposase from the external source so this is all the Non Autonomous type required. So yes, we can say that this transposon is able to move with its slightly changed DNA sequence.

gladiator answered 1 year ago

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