You have identified a Type 1 transposable element in yeast. This transposon has a small mutation...

You have identified a Type 1 transposable element in yeast. This transposon has a small

mutation that inactivates its only protein-encoding gene. If you provide this transposon

with an external source of transposase, would you expect this transposon to be able to

move?

Why or why not?

Expert Solution

Ans: Type 1 transposable elements are also known as retrotransposons and acts by copy and paste mechanism. This means that the original transposons remain in place while a copy inserted at the new position. In retrotransposons first the DNA is transcribed into RNA and this RNA copies itself and the new copy reverse transcribed into cDNA and inserted in the genome using the enzyme transposase.

We can also classify transposons into Autonomous (they have everything they need to promote their own transposition) and Non Autonomous ( they dont have functional transposase enzyme and require transposase from the others for transposition). So in the question it is given that the mutation inactivates its only protein coding gene so this retrotansposon converts to Non autonomous type. We are providing transposase from the external source so this is all the Non Autonomous type required. So yes, we can say that this transposon is able to move with its slightly changed DNA sequence.

gladiator answered 1 year ago

You have identified a mutation in a gene that results in enhanced drought resistance in tomato....

You have identified a mutation in a gene that results in enhanced drought resistance in tomato. It appears to encode a transporter. What will you have to do to determine whether the protein is associated with passive, active, or secondary active transport?

You have recently identified a maternal effect mutation in Xenopus that results in a complete lack...

You have recently identified a maternal effect mutation in Xenopus that results in a complete lack of endoderm. You map the mutation and find two genes with point mutations that change the amino acid sequence in the protein, but don’t know which mutation is causing the phenotype. Both genes have unknown functions. Design an experiment or series of experiments that would allow you to 1) discern which gene is the cause of the mutation, 2) determine if it most likely...

You have discovered a new galaxy and you think you have identified an Type II Cepheid...

You have discovered a new galaxy and you think you have identified an Type II Cepheid star with a period of 30 days. You measure its brightness and with the Period-Luminosity function you calculate the distance to the galaxy d. However, you later find out that in fact the star you had identified is a Type I Cepheid. Is the galaxy further than, or, close to, us than we previously expected? By what factor should you multiply d to get...

What effect does mutation at nucleotides within a silencer element have on the expression of the...

What effect does mutation at nucleotides within a silencer element have on the expression of the gene associated with the silencer? Why does it have this effect?

Jonathan has been diagnosed with a somatic mutation that has lead to Type 1 Diabetes Mellitus....

Jonathan has been diagnosed with a somatic mutation that has lead to Type 1 Diabetes Mellitus. The risk of his offspring inheriting this mutation from him is

You run a small private equity firm that specializes in identifying profitable acquisitions. You have identified...

You run a small private equity firm that specializes in identifying profitable acquisitions. You have identified the small, poorly managed, but profitable company GreenWatches, which has the following characteristics: ROE=7.5%, k=10%, b=60%, E1=3. a. Just from these values, how do you know that GreenWatches is poorly managed? b. What is the price (intrinsic value) of the stock and what is the current PVGO of the company? Why is the PVGO negative? You believe that you can turn around the company...

25.You are studying a new type of cancer and you discover that there is a mutation...

25.You are studying a new type of cancer and you discover that there is a mutation in a gene that encodes a histone acetylase. You hypothesize that the mechanism by which this mutation causes cancer is: A – Introducing random mutations B – By altering the expression of a gene involved in the control a cell proliferation C – Mutating DNA repair genes D – By introducing a mutation in a gene involved in the control a cell proliferation 26.Often...

A. You have your own p53 gene sequenced and notice that you have 1 mutation in...

A. You have your own p53 gene sequenced and notice that you have 1 mutation in the portion of the protein that binds to DNA. You also notice that the mutation is a silent mutation. Are you at a higher risk then someone with wild type p53 to develop p53 related cancers? Explain your answer in 1 sentence.

What evidence could you collect to confirm that the mutation identified in Sam’s DNA causes symptoms...

What evidence could you collect to confirm that the mutation identified in Sam’s DNA causes symptoms of RP?

Differentiate between an input element of type text and a textarea element, indicating where you would...

Differentiate between an input element of type text and a textarea element, indicating where you would be most likely to use each.

Question