What is a second-messenger system? Why is it necessary for amino
acid-based hormones to use such a system? Why does it allow amino
acid-based hormones to only act where they are supposed to?
Which hormones does the pituitary gland make? Which other glands
are directly controlled by the pituitary’s hormones? Why is it
beneficial that so many glands are controlled by a single organ
attached to the brain?
What is Hypoxia Inducible Factor (HIF)? What kind of situations
would cause...
What is Sherman Act and how does it differ from the Clayton
Act?
How did Rockefeller make his money?
Why was it seen as monopoly?
Did he still benefit from his company being dismantled? If so,
how?
Describe his upbringing.
Inositol 1,4,5-trisphosphate (IP3) and diacylglycerol
(DAG) are second messenger molecules derived from the cleavage of
the phosphatidylinositol-4,5-bisphosphate (PIP2) by activated
phospholipase C.
A) Describe the role of IP3 in causing a rise in
cytosolic Ca2+ concentration.
B)How do cells restore resting levels of cytosolic Ca+2?
C)What is the principal function of DAG?
Cytosolic Ca2+ is an important “second messenger”, and is
usually maintained at sub-micromolar concentrations. List 3
distinct mechanisms through which the cytosolic concentration of
Ca2+ is regulated.
2. Tumor-promoting phorbol esters such as TPA mimic the lipid
second messenger diacylglycerol. The tumor promoting effects are
most likely due to the suppression of TGF beta signals.
true or false