- Complex molecules are synthesized used chemical reactions; in
this reaction, a chemical bond is formed when water is removed. The
reaction that is used to complex molecules into simpler building
blocks is called catabolic reactions. In this reaction, bonds are
broken when _____is added. Reactions go faster when added
catalysts_.
Carbohydrates
- The simplest carbohydrates are called Monosaccharides.Three
common hexoses are Glucose,Fructose,Galactose,Mannose.Sucrose is
formed when Glucose +Fructose, Lactose is formed when
Glucose+Galactose, and maltase is formed when Glucose +Glucose
(alpha-1,4-linkage)These three molecules are examples of
Disaccharides. Humans and other animals store polysaccharides in
the form of glycogen. Plants store polysaccharides as starch.
Lipids
- Triglycerides are formed by the reaction of desertification of
fatty acids to glycerol.This form of lipid is used for steroids and
PGs.
- Phospholipids are formed by the combination of glycerol,
phosphoricacid,phosphate group. This form of lipid is mostly found
in cell membranes where they form lipid bilayers.
- Cholesterol
- Cholesterol is used to form _ hormones and vitamins_ such as
vitamins D and membranes_.
- Cholesterol and other lipids are transported by
lipoproteins.
- High levels of LDL is associated with increased risk of heart
disease whereas high levels of HDL is associated with improved
cardiovascular health.
Proteins
- Proteins are made up of amino acids. There are 21 amino acids
which differ by the chemical nature(acidic,basic,neutral). Amino
acids that can’t be synthesized by the body are called essential
ammino acids; they must be obtained from the diet. Amino acids
joined by peptide bond.
- The order of the amino acids in a protein is called its primary
structure. Examples of secondary structure include alpha helix,beta
pleated sheet. Tertiary structure are is formed by H- bonds,ionic
interactions, disulphide bonds. Quaternary structure is formed when
protein sub units binds
Transport Across Cell Membranes
Passive and Active Transport
- Passive transport across the cell membrane (requires/doesn’t
require) ATP while active transport (requires/doesn’t require) ATP.
Passive transport always occurs (down/against) the concentration
gradient. Active transport always occurs (down/against) the
concentration gradient
Diffusion
- Diffusion is the movement of molecules from an area of high
conc_ to an area of low conc This is an example of passive
transport. The rate of diffusion can be increased by conc gradient
.
Osmosis and Osmolarity
- Osmosis is the movement of solvent from less to more conc. The
osmolarity of a solution is defined as the total no.of solute
particles per liter. The normal osmolarity of body fluids is 306m
osmoles per lit. Iso-osmotic solutions have an osmolarity of
300-312 ; hypoosmotic solutions have an osmolarity lower and
hyperosmotic solutions have an osmolarity of greater.
- Hyper solutions cause water to enter cells which may cause
bursting_; hyposolutions cause water to leave cells which may cause
shrinkage and isotonic_ has no net effect of water
movement across the cell membrane
Vesicular Transport
- __________ is used to move materials into the cell. This
includes _________ and _________. The process that expels materials
from the cell is called _______.
Nucleic Acids, Transcription, Translation, Replication
Nucleic Acids
- Nucleic acids are made up of nucleotides, phosphate
group,sugarmoiety_. The two forms of nucleic acid are DNA and
RNA.
- DNA is made of nucleotides. The strands of DNA are held
together by H bonds_bonds between bases. Each adenine base is
paired with a thyamin; and each guanine is paired with a cytocine.
This form of base-pairing is called watson and crick_. DNA is
organized as coils inside the nucleus. The regions of the genome
that code for a protein is called a extron_.
- RNA is made of ribonucleotides It is (single/double) stranded
mRNA_ carries the codes that are responsible for making a protein.
tRNA transports amino acids; and rRNA is a part of the ribosome.
There are 64 codons which are formed by nucleotides. Codons code
for amino acid.
Transcription
- Transcription describes the process of copying DNA into mRNA.
The enzyme responsible for transcription is RNA polymerase_. This
process occurs in the cytoplasm. A single mRNA may code for several
proteins due to triplet codind__ which is used to remove noncoding
regions called introns.
Translations
- Translation is the process of protein synthesis. The mRNA
strand is read by the template _ which assembles the ribosomes. The
three steps of translation are initiation, elongation,termination_.
This process primarily occurs in the cytoplasm_.
DNA replication
- DNA replication occurs in the nucleus. In this process the DNA
is unwounded by topoisomerases. and it is then copied by DNA
polymerase. At the end of the process each new double-stranded
DNA