In: Anatomy and Physiology
As compared to blood how much acid concentration is needed in the stomach. How is it achieved. Describe the cell hormone enzymes that participate in the process
Acid concentration that is reached in the stomach at the highest is 159 mm. It is three million time's stronger than the arterials blood of human body
The pH of acid secretion in stomach is 0.8 which get diluted by secretion to 2-3 pH
This pH is mainly achieved by the hydrochloric acid secreted from the parital cells of our gastric glands .
It is an active process and energy for this is derived from Glucose oxidation.
From the metabolic activity of parital cells Co2 is derived and some Co2 from blood moves into parital cells. The enzyme CARBONIC ANHYDRASE helps in the combination of co2 with water and form carbonic acid . High concentration of carbonic anhydrase is there in parital cells and the carbonic acid is highly unstable so it divide into hydrogen ion and bicarbonate. The hydrogen ion moves into the canaliculus of the parital cells . Along with this the NACL from blood is pumped into the canaliculus that makes the cl to combine with hydrogen ion and for hydrochloric acid
Co2+H2O+ NACL -> HCL+ NAHCO3
This is how pH is maintained