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In: Anatomy and Physiology

- A 38-year-old male is upset about his low sperm count and visits a "practitioner" who...

- A 38-year-old male is upset about his low sperm count and visits a "practitioner" who commonly advertises his miracle cures of sterility. The practitioner is a quack who treats conditions of low sperm count with megadoses of testosterone. Although his patients experience a huge surge in libido, their sperm count is even lower after hormone treatment. Explain why.

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Expert Solution

Sperm is the male reproductive cell that is produced in the testes by GnRh from the hypothalamus. This stimulates the anterior pituatary to Follicle stimulating hormone (FSH) and Luteinising hormone(LH). LH stimulates the production of testosterone and FSH stimulates testicular growth and enhances the production of an androgen-binding protein by the Sertoli cells. This means LH and FSh works together to stimulate spermatogenesis.

Without both FSH and Androgen Binding Protein, testosterone has no effect on the testes. So, The libido increases because testosterone stimulates the brain and boosts the sex drive.

There will decrease in sperm count even more after taking these medicines because the excess level of testosterone will have negative feedback effects. This will reduce GnRH secretions and so secretion of LH and FSH will also be reduced which will cause inhibition of spermatogenesis. Sertoli cells will also inhibit spermatogenesis.

Sydney Mullin answered 1 year ago
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